AI Reads Routine Pathology Slides to Predict Cancer Biomarkers Across 12 Tumor Types
Researchers developed RIDGE, a weakly supervised deep learning system that predicts gene expression signatures and biomarkers such as microsatellite instability ...
Tag: TCGA
AI Framework Cleans Batch Noise From DNA Methylation Data to Sharpen Cancer Subtyping
Researchers have developed meth-SemiCancer2, a deep learning framework that combines domain adaptation and contrastive learning to correct batch effects in ...
Immune Checkpoint VISTA Doubles as a Growth Engine Inside Mesothelioma Cells
New research shows the immune checkpoint molecule VISTA also drives proliferation within mesothelioma cells through RIPK1-associated and AKT-dependent signalling, making ...
CASP9 Emerges as a Double-Edged Gene in Kidney Cancer, Study Finds
A multi-omics study identifies CASP9 as a genetically protective but stage-dependent prognostic factor in clear cell renal cell carcinoma, linking ...
RNA Splicing Errors in Drug Transporter Genes May Predict Cancer Survival Across 33 Tumor Types
A sweeping multi-omics study links alternative splicing of ABC transporter genes to survival across 33 cancer types and confirms causal ...
Ribosomal Protein RPL28 Emerges as a Driver and Prognostic Marker in Kidney Cancer
New research shows that the ribosomal protein RPL28 is overexpressed in clear cell renal cell carcinoma, where it independently predicts ...
Cancer Gene Duo Reveals Why Head and Neck Tumors Shrug Off Cisplatin
New research links the SERPINE1–CA9 gene axis to both aggressive growth and cisplatin resistance in head and neck squamous cell ...
One Tiny RNA, Many Cancers: Meta-Analysis Confirms miR-221 as a Pan-Cancer Killer Signal
A pan-cancer systematic review and meta-analysis links elevated microRNA-221 to significantly worse survival across multiple tumor types and maps its ...
Lab-Grown Brain Tumor Organoids Build Their Own Blood Vessels and Scaffolding
Researchers have grown glioblastoma organoids without any exogenous scaffold, allowing tumor stem cells to autonomously assemble neurovascular-like structures and extracellular ...
PTPN6 Gene Emerges as Potential Prognostic Marker in Bladder Cancer
A new bioinformatics study links PTPN6 overexpression and promoter hypomethylation to overall survival in bladder cancer, positioning the gene as ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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