Negative Controls Reveal Hidden Biases in Real-World Vaccine Effectiveness Studies
A PEDSnet study of adolescents shows that negative control outcomes used to detect bias in vaccine effectiveness studies are only ...
Tag: SARS-CoV-2
Training Immunity Against Variants That Do Not Yet Exist: A 600-Mutant Vaccine Strategy
A new mRNA vaccine strategy called Proactive Immune Training primes the immune system with one antigen and boosts it with ...
SARS-CoV-2 Enzyme NSP14 Disrupts DHX15-RIG-I Partnership to Silence Antiviral Alarm
New research shows that the SARS-CoV-2 enzyme NSP14 suppresses interferon production by binding the helicase DHX15 and disrupting its cooperative ...
Virtual Screen of 69,000 Natural Compounds Yields New SARS-CoV-2 Protease Inhibitor
A structure-guided screen of nearly 70,000 natural product-like compounds has produced STOCK1N-86169, a new low-micromolar inhibitor of the SARS-CoV-2 main ...
Pandemic Quietly Eroded Timely Breast Cancer Care at Mexico’s Leading Cancer Center
A retrospective cohort study at Mexico's National Cancer Institute finds that although overall treatment intervals appeared stable during the COVID-19 ...
Aging Blunts a Protective Gut Lipid Defense That Keeps COVID-19 Mild
New research in aged hamsters shows that COVID-19 severity may hinge on an age-dependent failure of the gut to produce ...
Computational Protein Design Supercharges Engineered Immune Cells Against Cancer and Viruses
Researchers at Bar-Ilan University and the Weizmann Institute used computational protein design to create an enhanced T-cell receptor, called SET, ...
Black Seed Shows Promise Against COVID-19 in Pooled Analysis of Randomized Trials
A new meta-analysis of six randomized controlled trials finds that Nigella sativa significantly reduced mortality, severe symptoms, and C-reactive protein ...
Hybrid-Capture Sequencing Turns Wastewater Into Strain-Resolved Multi-Virus Surveillance Tool
A 31-month hybrid-capture metagenomic study of wastewater in Leuven, Belgium recovered 339 viral species and 715 strains, showing that sewage ...
Microfluidic Method Boosts mRNA Vaccine Potency by Controlling Nanoparticle Architecture
A microfluidic technique that arranges metabolic and therapeutic RNAs in defined layers inside lipid nanoparticles raises ATP levels, boosts translation, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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