Liposomal Paclitaxel With HER-2 Blockers Shows Strong Real-World Results in Advanced Breast Cancer
A real-world study of 526 patients found that paclitaxel liposome combined with anti-HER-2 targeted therapies delivered median overall survival of ...
Tag: Progression-Free Survival
Antibody-Drug Combination Falls Short in First-Line PD-L1-High Metastatic Lung Cancer Trial
The Phase 3 EVOKE-03/KEYNOTE-D46 trial found that sacituzumab govitecan plus pembrolizumab did not significantly improve progression-free or overall survival compared ...
Timing Matters: Radiotherapy Within Six Weeks Reshapes Outcomes After Incomplete Spinal Ependymoma Surgery
A decade-spanning multicenter study shows that adjuvant radiotherapy delivered within 1.5 months of incomplete spinal ependymoma surgery dramatically reduces early ...
Simple Blood Scores May Predict Survival in Newly Diagnosed Multiple Myeloma
A combined blood-based inflammation and nutrition score strongly predicted survival outcomes in newly diagnosed multiple myeloma patients, improving risk stratification ...
Immune Side Effects May Signal Stronger Tumor Shrinkage and Longer Survival in Gastric Cancer
A Japanese study found that immune-related adverse events during checkpoint inhibitor therapy for advanced gastric cancer were independently linked to ...
Longer Gaps Between Tarlatamab Doses Show Promise in Small Cell Lung Cancer
The randomized Phase 2 DeLLphi-309 study found that extended-interval tarlatamab dosing every three or four weeks produced efficacy, safety and ...
Common Blood Marker CEA Predicts Outcomes in Prostate Cancer Radioligand Therapy
A prospective study of 142 patients finds that elevated baseline CEA independently predicts shorter survival in men with metastatic castration-resistant ...
ROS1 Fusion Subtype Shapes Survival in Advanced Lung Cancer, Real-World Data Show
A real-world study of 55 patients with advanced ROS1-rearranged non-small cell lung cancer shows that fusion subtype, PD-L1 expression and ...
Triple-Drug Antibody-Drug Conjugate Strategy Shows Promise in Hard-to-Treat Breast Cancer
A real-world study of 87 patients suggests that combining Trop-2 antibody-drug conjugates with PD-1 inhibitors and anti-angiogenic therapy substantially improves ...
Hidden ESR1 Mutations Signal Trouble Before Breast Cancer Progresses
A large U.S. real-world study found that ESR1 mutations emerging during first-line therapy for ER-positive metastatic breast cancer are linked ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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