Third Course of Stereotactic Radiotherapy Shown Safe in Spinal Osteosarcoma Case
A case report from Warsaw describes the first documented second reirradiation with stereotactic body radiotherapy in metastatic osteosarcoma, achieving a ...
Tag: osteosarcoma
Patient-Balanced Single-Cell Analysis Separates Recurring and Patient-Restricted Tumour Programmes in Osteosarcoma
A patient-balanced single-cell study of osteosarcoma resolved seven malignant programmes, separating a moderately recurrent extracellular-matrix state from a chondro-hypoxia programme ...
Ginsenoside RK3 triggers ferroptosis in osteosarcoma cells and boosts doxorubicin response
A preclinical study reports that ginsenoside RK3 suppressed osteosarcoma growth in cells and mouse xenografts by downregulating PRMT5, promoting GPX4 ...
Osteosarcoma rewires matrix signaling as disease progresses
A 2026 Review argues that osteosarcoma survival and lung spread depend on stage-specific rewiring of extracellular-matrix signaling rather than one ...
Review assesses miRNA nanocarriers for osteosarcoma
A 2026 review finds that miRNA nanocarriers may help overcome delivery barriers in osteosarcoma, while emphasizing unresolved safety, manufacturing, regulatory ...
EP300 Degradation and AKT Inhibition Slow Osteosarcoma in Preclinical Models
A PROTAC that degrades EP300 combined with AKT inhibition slowed tumor growth and extended survival in patient-derived osteosarcoma mouse models, ...
Thai researchers outline early-phase trial of a new GD2 CAR-T product
A published protocol describes a planned first-in-human trial of an investigational product: an autologous chimeric antigen receptor T-cell therapy designed ...
Single-cell and bulk transcriptomic characterization of the osteosarcoma microenvironment reveals lineage-specific programs and inflammatory differences associated with metastasis
Osteosarcoma has long frustrated oncologists. It is the most common primary malignant bone tumor, striking hardest in adolescents, and while ...
Stem Cell Gene Sox2 Study in Bone Cancer Retracted Over Manipulated Images
The journal Pathology & Oncology Research has retracted a 2018 osteosarcoma study after the authors reported improper image cropping, with ...
Rare Sarcoma Brain Metastases Show Striking Imaging Signatures on MRI Scans
A systematic analysis of 22 patients reveals that intracranial sarcoma metastases are strikingly heterogeneous on CT and MRI, with candidate ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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