Low Oxygen Turns Inflammatory Switch That Drives Oral Cancer Growth
New research in the British Journal of Cancer shows that oxygen-starved oral cancer cells activate an HMGB1-driven NLRP3 inflammasome pathway ...
Tag: oral squamous cell carcinoma
Cellular Stress Hubs Help Oral Cancer Spread, Study Finds
New research shows that stress-induced eIF2α phosphorylation drives stress granule formation that promotes growth and metastasis in oral squamous cell ...
Scientists Uncover How Oral Cancer Cells Outsmart Cisplatin by Blocking Ferroptosis
New research reveals that the secreted protein DKK1 helps oral squamous cell carcinoma resist cisplatin by keeping the SLC3A2 cystine ...
Betel Nut Chemical Shields Oral Cancer Cells From Copper-Driven Cell Death
New research shows that arecoline, the main alkaloid in betel nut, activates a ROS-NRF2-MT2A signaling axis that protects oral squamous ...
Gene Variants That Detoxify Tobacco Carcinogens Reshape Oral Cancer Risk
A critical review of 21 studies finds that inherited variants in carcinogen-metabolizing enzymes, especially GSTM1 and GSTT1 null genotypes, modulate ...
Metadherin emerges as an invasion switch in oral squamous cell carcinoma
New research shows that metadherin, enriched at the invasive front of oral squamous cell carcinoma, drives tumor invasion by selectively ...
Lingonberry Extract Starves Oral Cancer Cells by Rewiring Their Energy Metabolism
A cold-pressed lingonberry extract selectively inhibited the proliferation and invasion of oral cancer cells in laboratory experiments by disrupting the ...
Injecting the Immune System: Long-Acting TLR7/8 Agonist Shows Promise Against Oral Cancer
A small German cohort study reports that injecting a slow-release TLR7/8 agonist into oral tumors before surgery, combined with systemic ...
Spit Test for Oral Cancer? Saliva miRNAs and Cell Markers Show Promise in Tobacco Users
A pilot study finds that salivary miR-31-5p and EGFR expression in oral exfoliated cells are dramatically deregulated in tobacco users ...
From Bench to Bedside: New Tools Push Veterinary Oral Cancer Toward Targeted Therapy
New spatial transcriptomics, patient-derived models, and comparative clinical trials of trametinib and a STAT3 decoy are transforming the treatment of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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