Genetic Testing and Targeted Therapy Benefit Lung Squamous Cell Carcinoma Patients
A retrospective study of 1,515 patients indicates that genetic testing and targeted therapy enhance clinical outcomes and reduce healthcare costs ...
Tag: oncology
Blocking FANCD2 Restores Ferroptosis Sensitivity to Counter Enzalutamide Resistance in Prostate Cancer
Targeting the DNA repair protein FANCD2 overcomes enzalutamide resistance in prostate cancer models by disrupting antioxidant defenses and reactivating iron-dependent ...
Healthcare Providers Identify Key Drivers of Diagnostic Delay in Breast Cancer
A qualitative study of thirty healthcare providers identifies five major categories of individual, socio-cultural, and healthcare system factors contributing to ...
Swedish Regional Chemotherapy Disparities Linked to Survival Differences in Older Breast Cancer Patients
A nationwide Swedish cohort study of 61,935 women with HR+/HER2- early breast cancer revealed substantial regional variation in chemotherapy use ...
Immune Checkpoint and Anti-EGFR Regimen Evaluated in Head and Neck Cancer
A retrospective study reports clinical activity and manageable safety for immune checkpoint inhibitors combined with anti-EGFR agents in recurrent or ...
METTL16 Epigenetic Axis Drives Liver Cancer Growth and Cisplatin Resistance
Researchers revealed that the RNA methyltransferase METTL16 cooperates with IGF2BP2 to stabilize LAMA4 and upregulate COL4A1, accelerating hepatocellular carcinoma progression ...
Family Caregivers Face Pervasive Systemic Struggles in Incurable Gastrointestinal Cancer
A qualitative study in BMC Palliative Care reveals that family caregivers of patients with incurable oesophageal or gastric cancer endure ...
PGK1 Expression Associates With Overall Survival in TCGA Breast Cancer Cohort
In an observational analysis of the TCGA-BRCA cohort, elevated tumor PGK1 expression was associated with shorter overall survival, though researchers ...
Tumor Multiplicity and Location Predict Bladder Inverted Papillary Tumor Recurrence
A retrospective cohort study found that tumor multiplicity and extra-trigonal location independently predict recurrence in patients with low-grade inverted papillary ...
Mixed-Methods ACTION Study Evaluates General Practitioners in German Cancer Aftercare
Researchers have established the protocol for the ACTION project, a thirty-month mixed-methods investigation evaluating general practitioner involvement in oncological aftercare ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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