Tag: NF-κB

A preclinical study demonstrates that sericin attenuates cognitive impairment and hippocampal inflammation in diabetic rats through the PI3K/AKT signaling pathway.

Tibetan dark tea alleviates experimental ulcerative colitis in laboratory models by suppressing inflammation, reducing TXNRD-dependent ferroptosis, and remodeling the gut ...

In diabetic mice, berberine alleviated cognitive impairment by reducing 4-HNE adduct formation and activating the hippocampal PI3K/AKT/mTOR insulin signaling pathway.

Researchers evaluated two clerodane diterpenes from Psidium guajava, finding that borapetoside F and borapetoside B inhibited carcinoma cell growth in ...

A basic science study reveals that TLR8 activation aggravates liver inflammation and fibrosis in biliary atresia by activating hepatic stellate ...

A review describes how reciprocal crosstalk between the IL-6/STAT3 and purinergic signaling pathways drives chronic inflammation, immune suppression, and therapy ...

A review in Molecular Biology Reports indicates that targeting the crosstalk between RIPK1-mediated necroptosis and NF-κB signalling could reduce neuroinflammation ...

A mechanistic review details how the STAT3 and NF-κB signaling axis in myeloid cells promotes immune evasion and immunotherapy resistance ...

In preclinical models of non-small cell lung cancer, circular RNA circLAMC1 suppressed tumor progression by regulating the miR-27a-3p/PAQR3/NF-κB/p53 signaling axis.

A retrospective study identified seven patients with coexisting amyotrophic lateral sclerosis and primary Sjögren’s syndrome alongside shared, non-specific inflammatory transcriptomic ...