Hemp Seed Cake Yields Two Natural Molecules That Block a Key Diabetes Enzyme
Scientists isolated two phenylpropionamide compounds from hemp seed cake that inhibit the diabetes-linked enzyme PTP1B in vitro, with kinetic, docking, ...
Tag: natural products
Plant Compounds Called Flavonoids Could Become Next-Generation Leukemia Drugs
A new computational Perspective argues that flavonoids, exemplified by the soy isoflavone daidzein, are a largely untapped and rationally designable ...
Plant Compounds Target Host Immune Signaling to Fight Influenza A Virus
A new review in MicrobiologyOpen details how plant-derived phytochemicals modulate TLR, RIG-I, MAPK, and NF-κB signaling to combat influenza A ...
Nearly All Norwegian Pakistanis Use Traditional and Complementary Medicine, Survey Finds
A large cross-sectional survey of Norwegian Pakistanis found that 99.8 percent used traditional or complementary medicine in the past year, ...
Two Coumarins From Korean Angelica Root Carry Most of Its Anti-Inflammatory Power
A new study shows that the two pyranocoumarins decursin and decursinol angelate reproduce the major anti-inflammatory and antioxidant effects of ...
AI Model Mines Fungal Chemistry for New Diabetes Drug Leads
Researchers in Thailand have built an interpretable stacked machine learning framework called Meta-iPPAR that accurately predicts PPAR-γ agonists and identified ...
Seagrass Microbes from Tanzania Hint at New Antibiotic Sources
Researchers in Tanzania have isolated seven endophytic Actinomycetota from the seagrass Oceana serrulata, six of which appear to be new ...
Plant-Derived Compounds Could Crack Osteosarcoma’s Chemotherapy Resistance by Triggering Ferroptosis
A new review in Molecular Diversity maps how plant-derived natural products can induce iron-dependent ferroptosis and remodel the immune microenvironment ...
AI Chatbots Redesign a Plant Molecule to Out-Bind a Gout Drug
Researchers used three AI platforms to structurally modify the natural compound beta-caryophyllene and computationally identified derivatives that bind xanthine oxidase ...
Bee Propolis Shows Potent Antifungal Power Against Drug-Resistant Candida
A systematic review of 62 studies finds that propolis exhibits broad-spectrum antifungal activity against Candida species, including azole-resistant strains, through ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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