Engineered NK Cells Target Hidden Cancer Antigen to Control Melanoma in Mice
Brazilian researchers engineered natural killer cells with a TCR-like CAR that recognizes an intracellular melanoma antigen displayed on HLA molecules, ...
Tag: natural killer cells
Engineered fusogenic vaccinia virus arms IL-15 to reprogram tumors and boost antitumor immunity
Researchers engineered a fusogenic oncolytic vaccinia virus that displays IL-15Rα on infected tumor cells to locally trans-present IL-15, reprogramming the ...
Natural Killer Cells Stay Battle-Ready in Obesity-Linked Cancer Terrain
Researchers at Trinity College Dublin report that KHYG-1 natural killer cells retain their cancer-killing function after exposure to the tumour ...
Midlife Obesity May Quietly Disarm the Body’s Natural Killer Cells
New research in Aging Cell shows that natural killer cell numbers, maturation, and antitumor function decline during midlife obesity, particularly ...
Natural Killer Cell Education Leaves Lasting Imprints on the Persistent HIV Reservoir
New research in Nature Immunology shows that KIR2DL1-educated natural killer cells leave durable imprints that shape which HIV-1 reservoir cells ...
Lab Models Take Center Stage in the Race to Improve Cancer Immunotherapy
A systematic review of 75 studies maps how organoids, spheroids, tissue slices, and tumor-on-a-chip systems are being used to test ...
Scientists Discover CD55 Is the Hidden Switch That Powers Natural Killer Cells Against Cancer
New research shows that CD55 acts as a self-sufficient ignition switch for natural killer cell attack on tumors, and that ...
Exercise May Turn Cold Tumors Hot and Boost Immunotherapy Response
A new review shows that physical exercise can remodel the tumor microenvironment to convert immunologically cold tumors into treatment-responsive ones ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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