How the Immune System Matures, Ages, and Defies Time
A new review maps how human immunity develops from a deliberately tolerogenic newborn state through adult peak performance to the ...
Tag: natural killer cells
Spatial Transcriptomics Maps the Cellular Battlefields of Fatal COVID-19 Lungs
A spatial transcriptomics study of fatal COVID-19 lungs reveals progressive loss of endothelial and immune cells, explosive peribronchial fibroblast expansion, ...
Master Switch PRDM1 Steers Natural Killer Cell Maturation and Cancer Defense
A new review details how the transcriptional repressor PRDM1 orchestrates natural killer cell maturation, effector function, and tumor suppression, with ...
Cell Cycle Timing Shapes How Natural Killer Cells Fire Their Weapons
A combined CyTOF and computational modeling study shows that NKG2D signaling and degranulation in human NK cells depend on the ...
Lipid Nanoparticles Reprogram NK Cells Inside the Body to Fight Cancer and Autoimmune Disease
MIT engineers have developed lipid nanoparticles that reprogram natural killer cells inside the body to destroy cancerous and autoreactive T ...
Cancer Gene Mutations Awaken the Immune System in Early Oral Cancer
Researchers at Tokushima University found that combined TP53 and CDKN2A mutations activate cGAS–STING-mediated antitumor immunity, delaying progression to invasive oral ...
Lipid nanoparticles reprogram natural killer cells inside the body to fight cancer
MIT researchers have engineered ligand-directed lipid nanoparticles that reprogram natural killer cells into CAR-bearing cancer killers directly inside living animals, ...
Immune Gene Profiles Linked to Higher EBV DNA Levels in Nasopharyngeal Cancer
A case-control study in southern China links the HLA-A*11:01-negative/KIR2DS4 Deleted/Deleted immune gene profile to significantly higher pretreatment plasma Epstein-Barr virus ...
Blocking a Single Protein Makes Childhood Cancer Cells Easier for Immunotherapy to Find
Penn State researchers found that blocking the protein VPS34 raises levels of the GD2 molecule on neuroblastoma cells, making them ...
Coumarin Supercharges Natural Killer Cells to Fight Liver Cancer, Study Finds
New preclinical research shows that the plant compound coumarin activates natural killer cells, boosts their mitochondrial energy supply, and shrinks ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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