Two-Drug Strike Cripples DNA Repair in Malaria Parasite
New research shows that inhibiting the chaperone PfHsp90 with 17-AAG destabilizes the malaria parasite's Bloom helicase PfBlm and potentiates the ...
Tag: malaria
Plant Alkaloids Hitch a Ride Into Malaria Parasite’s Stomach to Deliver a Lethal Blow
New research shows the plant alkaloids berberine and palmatine are ferried into the malaria parasite's digestive vacuole by the PfPgh-1 ...
How Mosquitoes Outsmart Insecticides: Resistance Mechanisms Reshape Disease Control
A comprehensive review maps the molecular, metabolic, behavioral, and microbiome-driven mechanisms of insecticide resistance in mosquitoes and outlines next-generation strategies ...
Tropical Tree Extracts Show Potent Larvicidal Power Against Major Disease-Carrying Mosquitoes
Nigerian researchers report that ethyl acetate extracts from Terminalia catappa leaves and Eucalyptus citriodora seeds and stems kill larvae of ...
Climate, Cities and Vanishing Forests Are Rewriting the Map of Vector-Borne Disease
A comprehensive review proposes a triaxial framework showing that climate change, deforestation, urbanization, and biodiversity loss interact synergistically to reshape ...
Targeting Malaria Interventions by Geography Could Stretch Scarce Health Budgets
A spatially explicit model of malaria transmission in southeastern Madagascar shows that community-based interventions targeted by geography can match district-wide ...
Falling platelets track malaria parasite burden in Ghana, but only up to a point
The finding that platelet counts decline progressively with advancing age across the study population deserves particular attention, because it complicates ...
Genomic surveillance reveals patchy mosquito resistance across Rwanda, reshaping malaria policy
A Rwandan policy brief argues that genomic surveillance of Anopheles gambiae resistance is essential to guide cost-effective, site-specific insecticide deployment ...
Kenya’s Malaria Parasites Largely Keep Genes That Rapid Tests Rely On, Study Finds
A study of 350 archived Kenyan blood samples finds that deletions of the pfhrp2 and pfhrp3 genes remain rare both ...
Malaria drug pipeline review finds promising compounds but few ready for the clinic
A systematic review of 252 studies published between 2024 and 2026 shows natural products dominating antimalarial discovery while warning that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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