Toad Venom Compound Cinobufagin Disables Liver Cancer Cells by Shutting Down Their Peroxisomes
A team in China reports that cinobufagin, the main antitumor component of traditional Chansu venom, collapses peroxisome biogenesis in liver ...
Tag: lipid metabolism
Scientists Link a DNA-Building Enzyme to Fat Rewiring and Chemotherapy Failure in Pancreatic Cancer
A new study identifies RRM2 as a gene that connects nucleotide metabolism and SREBP1/FASN-driven lipid remodeling to gemcitabine resistance in ...
The Schisandra-Salvia-Hawthorn herbal formulation demonstrates therapeutic efficacy in ameliorating hyperlipidemia
A carefully balanced trio of traditional medicinal herbs—Schisandra chinensis (magnolia vine fruit), Salvia miltiorrhiza (red sage), and hawthorn—may offer a ...
Tiny Hypothalamic Protein NPGM Redirects Energy From Reproduction to Fat in Quail
New research in Japanese quail shows that the hypothalamic protein NPGM promotes fat deposition and suppresses gonadal hormones through distinct ...
Bariatric Surgery Rewrites the Genetic Script of Fat Tissue, but a Stubborn Molecular Memory Remains
A detailed transcriptomic study of subcutaneous and visceral fat in women with severe obesity reveals that bariatric surgery partially restores ...
Ancient Chinese Formula Shields the Brain by Rewiring Gut Microbes and Metabolism
A multi-omics study shows that the classical Chinese formula Xijiao Dihuang Decoction protects rats against stroke reperfusion injury by remodeling ...
SIRT2: The NAD-Dependent Enzyme That Ties Metabolism to Aging
A new review highlights how the NAD+-dependent deacetylase SIRT2 regulates glucose, lipid, and mitochondrial metabolism while influencing inflammation, genome stability, ...
Oxidative stress emerges as central driver of steroid-induced femoral head necrosis
A new review argues that oxidative stress acts as a central amplifier connecting bone loss, vascular injury, apoptosis, inflammation, and ...
Mapping Cancer’s Fatty Footprints: Spatial Lipidomics Enters the Clinic’s Waiting Room
A new review maps how spatial lipidomics is reshaping the study of ovarian, endometrial, and cervical cancers while warning that ...
Yogurt Bacterium Extends Healthy Aging by Reprogramming Fat Metabolism in Worms
A new GeroScience study shows that the yogurt bacterium Streptococcus thermophilus extends healthspan in C. elegans by activating the NHR-49/delta-9 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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