Two blood markers together flag highest heart risk in UK Biobank study
An analysis of 286,025 UK Biobank participants found that low estimated glucose disposal rate combined with high lipoprotein(a) marked the ...
Tag: insulin sensitivity
Targeting Fat Cells With Sphingosine Kinase 2 Inhibitors Shows Promise Against Obesity in Mouse Studies
VCU Massey researchers found that blocking sphingosine kinase 2 specifically in fat cells reduced body weight and improved metabolic health ...
Blocking a Protein-Cleaving Enzyme Extends Lifespan and Health in Aging Mice
A small-molecule inhibitor of the asparagine-cleaving enzyme AEP was associated with longer survival, reduced frailty, better cognition, and improved metabolic ...
Black soldier fly meal alters liver fat and inflammation in mice
A 12-week trial in healthy male mice found that a 10% black soldier fly larval-meal diet reduced liver lipid-droplet area ...
Genetic Evidence Finds No Clear Vitamin D–Diabetes Link in South Asians
A two-sample Mendelian randomization study using South Asian genetic data found no statistically significant association between genetically predicted vitamin D ...
Higher eGDR linked to lower gastrointestinal cancer mortality in UK cohort
A prospective UK Biobank study found that higher estimated glucose disposal rate was associated with lower gastrointestinal cancer mortality, but ...
Triglyceride–glucose index identifies early metabolic stress and β-cell vulnerability in pediatric obesity
A cross-sectional study in children and adolescents with obesity links higher triglyceride–glucose index values to impaired insulin sensitivity and potential ...
PET scans reveal how anorexia nervosa reshapes insulin sensitivity tissue by tissue
A Finnish PET imaging study maps insulin-stimulated glucose uptake across muscle, fat, liver, gut, and brain in women with anorexia ...
AI Screens 700,000 Natural Compounds to Find Molecule Behind Exercise’s Insulin-Boosting Power
A computational study combining multi-omics analysis and AI-driven drug discovery has identified WNT4 as a candidate molecular switch in exercise-mediated ...
Hypoxia Switch in Fat Cells Reveals How Obesity Locks In Lipid Storage
Deleting HIF1α in mature adipocytes shrinks fat cells and improves insulin sensitivity in obese mice by disrupting a PPARγ-driven pipeline ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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