Loss of a Single Splicing Protein Reshapes the Heart’s Scarring Response
Deleting the RNA splicing factor PTBP1 in cardiac fibroblasts reshapes the profibrotic response by altering alternative splicing of key fibrosis-related ...
Tag: heart failure
Cannabidiol Eases Heart Failure Damage by Rejuvenating Aging Cells and Restoring Organelle Communication
New research in mice shows that cannabidiol reduces cardiac fibrosis and diastolic dysfunction in HFpEF by clearing senescent cells, suppressing ...
Stiff Arteries and a Weakened Heart May Drive Poor Quality of Life Before Atrial Fibrillation Ablation
A new study links stiffer arteries, higher central blood pressure, and impaired cardiac function to poorer quality of life in ...
Sex Alone Does Not Define Heart Cell Defects in HFpEF, Review Finds
A new review finds that current evidence does not support using sex alone to define calcium- or titin-dominant HFpEF endotypes ...
Simple Blood Test Could Catch Heart Failure Early in People with Diabetes
Experts from ten countries report on real-world efforts to implement ADA-recommended NT-proBNP screening for early detection of asymptomatic heart failure ...
Ketone Bodies That Never Fall: A Warning Sign for Failing Hearts
Repeated blood measurements show that persistently elevated ketone bodies independently predict death and rehospitalization in heart failure patients across two ...
AI Predicts Which Heart Failure Patients Will Return to the Hospital Within 30 Days
An interpretable machine learning model trained on 20 years of rural Spanish registry data outperforms logistic regression in predicting 30-day ...
Adults With ADHD Face Steep Cardiorenal Risks Even After Starting Blood Pressure Drugs
A nationwide Dutch cohort study of more than 700,000 adults finds that those with ADHD experience significantly higher rates of ...
Cytosolic NADPH Emerges as the Molecular Signal That Lets the Heart Mimic Exercise
New research in Nature Metabolism shows that raising cytosolic NADPH, a pentose phosphate pathway metabolite, recreates the heart-protective effects of ...
Extra Pounds May Defy Expectations in Heart Failure, With or Without Diabetes
A large Korean cohort study shows that overweight heart failure patients survive longer than lean patients regardless of diabetes status, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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