Astrocytes may drive chronic traumatic encephalopathy, scoping review finds
A PRISMA-guided scoping review of 40 studies argues that astrocytes act as early, active contributors to chronic traumatic encephalopathy rather ...
Tag: glymphatic system
Brain MRI marker tracks tissue chemistry, not Parkinson’s severity
A multimodal MRI study of 76 Parkinson's patients found the DTI-ALPS index covaried with regional thalamic tissue susceptibility and age ...
Crossing the Blood-Brain Barrier Is Only the First Step for CNS Drugs
A new review argues that crossing the blood-brain barrier is only the starting point of CNS drug delivery, with perivascular ...
MRI Index Tied to the Brain’s Waste Clearance System May Be Misleading in Epilepsy
A study of 79 people with drug-resistant focal epilepsy found no significant DTI-ALPS index differences versus healthy controls, but lesion ...
Light Therapy Works Only During Sleep in Aging Mouse Brains
A study in mice finds that near-infrared light therapy clears beta-amyloid and improves memory in aged animals only when delivered ...
Dexmedetomidine Faces a Reality Check as Evidence Points to Conditional Benefits
A new editorial argues that recent large trials have failed to show broad benefits for the sedative dexmedetomidine, while suggesting ...
Brain ventricle size drives variability in a popular MRI marker of fluid transport
A cross-sectional study of 784 women found that lateral ventricular volume, not reproductive hormones, statistically accounted for most variation in ...
Tau, Not Just Amyloid, May Drive the Fast Cognitive Hits of Sleep Loss, Researchers Argue
A new opinion article in Frontiers in Neurology argues that tau-related mechanisms, which respond rapidly to sleep loss, deserve far ...
The interplay between chronobiology, neuroinflammation, and the glymphatic system in neurodegenerative diseases
A conceptual review proposes that disrupted circadian timing may reinforce neuroinflammation, impair glymphatic clearance and alter molecular clock activity.
DTI-ALPS links more consistently with cognition in asymptomatic moyamoya disease
In a cross-sectional study of 59 people with asymptomatic moyamoya disease, DTI-ALPS was more consistently associated with global cognition than ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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