Iron’s Dark Side: How Ferroptosis Drives Brain Disease and What Could Stop It
A new review proposes the Iron-Brain Nexus framework to explain why the brain is uniquely vulnerable to iron-dependent ferroptotic cell ...
Tag: glutathione
The humble mucus drug N-acetylcysteine may be medicine’s most versatile repurposing candidate
A scoping review of 140 reviews finds N-acetylcysteine studied across 17 clinical domains, but widespread low-quality and redundant evidence still ...
Scientists Uncover How Oral Cancer Cells Outsmart Cisplatin by Blocking Ferroptosis
New research reveals that the secreted protein DKK1 helps oral squamous cell carcinoma resist cisplatin by keeping the SLC3A2 cystine ...
Machine Learning Links a Mother’s Milk Diet to Her Child’s Language Skills
A pilot machine learning study of 20 mother-child dyads found that maternal lactation nutrients such as phosphatidylcholine, glutathione, and glycemic ...
Triaptosis: Scientists Unveil a New Form of Cell Death Centered on Endosomes
A new review in Cell Death & Discovery proposes triaptosis, an endosome-centered form of ROS-regulated cell death driven by oxidative ...
Astrocyte Redox Switch Linked to Synapse Damage in Multiple Sclerosis
A new single-cell and animal study links SLC7A11-high astrocyte states to antioxidant failure and synaptic remodeling in multiple sclerosis, pointing ...
Blood Test for Antioxidant Capacity May Predict Recovery From Bipolar Mania
A four-week follow-up study of 70 patients with bipolar mania found that changes in total antioxidant capacity significantly predicted symptomatic ...
Splicing Factor LUC7L2 Emerges as a Driver of Kidney Damage from Chemotherapy
New research reveals that the RNA splicing factor LUC7L2 drives ferroptotic kidney damage from cisplatin by corrupting the splicing of ...
When Oxidants Meet Telomeres: A Rigorous Audit of Redox Control in Cancer
A new critical review argues that much of the apparent conflict in the redox–telomerase literature reflects experimental design flaws rather ...
Cheap Antioxidant Mouthwash Cuts Severe Oral Damage in Stem Cell Transplant Patients
A double-blind randomized trial found that an inexpensive N-acetylcysteine mouthwash significantly reduced severe oral mucositis in hematopoietic cell transplant recipients, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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