New Data Structure Slashes Memory Overhead for Genomic Index Rank Queries
Computer scientists have developed paired-block bit vectors and flattened bit vectors that cut rank-query memory overhead to 1.6 percent and ...
Tag: genomics
Polynesian genomes reveal rare variants shaping gout, diabetes and blood lipids
Whole-genome sequencing of 1,043 French Polynesian participants reveals hundreds of variants absent from global reference datasets that shape metabolites, gene ...
Small neural network sharpens gene alignment across species
A compact deep-learning model called minisplice learns splice signals across vertebrates and insects and, when integrated into minimap2 and miniprot, ...
Massive Single-Cell Map Reveals How Rare and Common Gene Variants Steer Immunity
Phase 1 of the TenK10K consortium maps common and rare genetic variants affecting gene expression across 28 immune cell types ...
Genomics Goes Routine: From Model Labs to Honey Bees, Crops and Wild Populations
A new perspective argues that genomics has shifted from a specialized pursuit of well-funded labs to a routine tool now ...
AI Shows Promise for Multiple Sclerosis Diagnosis, Review Finds Validation Gaps
A systematic review of 26 studies finds AI models diagnosing multiple sclerosis with over 95 percent accuracy in some cases, ...
Genomes of Two Brazilian Estuarine Cyanobacteria Reveal Fatty Acid Production Secrets
Whole-genome sequencing of two Aphanothece strains from a Southern Brazilian estuary reveals conserved lipid genes but strain-specific fatty acid outputs ...
JEEPERS Corrects Hidden Methylation Errors in Cell-Free DNA Sequencing
A new computational framework called JEEPERS detects and corrects methylation errors caused by jagged ends in cell-free DNA, improving cancer ...
Gharial genomes reveal ancient and recent population decline
The first genome-wide analysis of the gharial reveals extremely low genetic diversity in its largest population, driven by an ancient ...
22 Tea Plant Genomes Show Conserved ARR Subgroups and Shell Orthogroup Variation
A comparison of 22 chromosome-scale tea plant genomes found 979 ARR response-regulator genes, with conserved subgroups but variation concentrated in ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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