Common RT–qPCR Artifact May Inflate RNA Knockdown in CRISPR Experiments
New research shows that a pervasive RT–qPCR artifact can artificially inflate reported RNA knockdown by RNA-targeting CRISPR systems.
Tag: gene expression
Fruit Fly Genomes Reveal How Circadian Clocks Evolve and Adapt
A genome-wide eQTL analysis in Drosophila melanogaster maps the regulatory variants that shape circadian clock function and its capacity for ...
ABC Transporter Gene ABCG2 Emerges as a Dynamic Marker of Acute Pancreatitis Severity
A prospective clinical study finds that ABCG2 gene expression is suppressed in acute pancreatitis patients yet rises significantly with radiologically ...
Calcium Channel TRPV4 Emerges as a Key Player in Marfan Syndrome Aortic Disease
A new study identifies the mechanosensitive calcium channel TRPV4 as a top candidate driving the inflammatory and remodeling behavior of ...
Scientists Decode the Genetic Secrets of Eye Cancer in Hereford Cattle
The first whole transcriptome analysis of bovine ocular squamous cell carcinoma in Hereford cattle reveals overexpressed genes driving keratinization, inflammation, ...
Epigenetic Marks and Jumping Genes Decide Which Parental Genome Rules Mustard
New research shows that asymmetric DNA methylation, histone marks and transposable element insertions explain why one parental genome dominates gene ...
Scientists Pinpoint Wheat Genes That Fight Devastating Spot Blotch Disease
A large genome-wide association study of elite bread wheat has identified a stable chromosome 3BS locus and differentially expressed candidate ...
Tiny RNA Molecule Pushes Schistosome Parasites Toward Self-Destruction
Researchers report that the microRNA sja-miR-2a-3p is enriched in reproductive tissues of Schistosoma japonicum and promotes apoptosis-related gene expression and ...
Mole-Rat Genes Evolving Faster Than Expected Reveal Secrets of Subterranean Life
A new comparative multiomics study identifies hundreds of fast-evolving genes and regulatory elements in African mole-rats, revealing selection-driven changes linked ...
Four-Gene Signature Tied to Young Age Predicts Breast Cancer Recurrence Risk
A new study identifies a four-gene expression signature linked to young age that independently predicts recurrence risk in breast cancer.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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