PARylation Stabilizes AFF1 for Transcription Recovery Post-DNA Damage
In the intricate world of cellular biology, the ability to manage transcription under duress, particularly following DNA damage, is paramount ...
Tag: DNA damage response pathways
MED1 IDR Deacetylation Regulates Stress Response Genes
A newly published study sheds light on the intricate mechanisms governing gene expression in response to cellular stress, a phenomenon ...
FBXW7 Regulates CHK2, Influencing Huntington’s Disease
In a groundbreaking study that could reshape our understanding of neurodegenerative diseases, researchers have uncovered critical molecular mechanisms that govern ...
DNA2 Limits Recombination to Promote Growth
A newly uncovered mechanism reveals how DNA2, an enzyme long recognized for its role in DNA replication and repair, is ...
Breakthrough First-in-Class Covalent Werner Helicase Inhibitor Demonstrates Clinical Proof-of-Concept in Phase I Trial
In a landmark development in the field of oncology and targeted cancer therapies, researchers at The University of Texas MD ...
R-Loops: Double-Edged Players in Genome Stability and Disease
In the rapidly evolving landscape of molecular biology, R-loops—a three-stranded nucleic acid structure formed by an RNA:DNA hybrid and a ...
Insilico Medicine Unveils Innovative CDK12/13 Dual Inhibitors for Tumor Therapy with the Help of Generative AI
Insilico Medicine, a pioneering biotechnology company specializing in generative artificial intelligence (AI), has recently made significant strides in cancer treatment. ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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