Phenotype-Guided Angiotensin II Therapy Proposed for Vasodilatory Shock in Critical Care
A narrative review proposes combining clinical phenotypes with early hemodynamic assessment to guide targeted angiotensin II therapy in vasodilatory shock.
Tag: critical care
Bicarbonate May Reduce Dialysis Needs in Critically Ill Patients
A Bayesian meta-analysis of four randomised trials indicates that sodium bicarbonate may reduce the need for dialysis in critically ill ...
Machine Learning Model Predicts Kidney Recovery From 72-Hour Urine Output Trajectories
A retrospective cohort study found that late-phase urine output variability over 72 hours predicted 28-day renal recovery in continuous kidney ...
Sustained oxygenation and pressure burdens linked to higher mortality in ventilated ICU patients
A retrospective MIMIC-IV landmark study of 18,285 ventilated adults found that sustained early oxygenation deficits and elevated driving-pressure proxies were ...
Ulinastatin Shortens ICU Stays in Post-Traumatic Sepsis Trial
A randomized controlled trial found that ulinastatin was associated with shorter ICU and hospital stays and improved inflammatory markers in ...
ICU GHB Infusion Linked to Deeper Sleep
A recent study in Critical Care reports that intravenous gamma-hydroxybutyrate is associated with deeper, more efficient sleep in awake ICU ...
Cardiovascular Collapse in Septic Shock Traced to Ventricular Mismatch and Math Artifacts
A scientific re-evaluation reveals that paradoxical cardiac output declines during vasopressor titration in septic shock stem from acute ventricular afterload ...
Endothelial Activation and Stress Index Linked to Mortality in Stroke ICU Patients
A retrospective cohort study of 1,647 intensive care patients with acute cerebral infarction found that higher scores on the Endothelial ...
Why standardizing pneumonia response alone cannot define treatment effect in trials
A Critical Care letter argues that standardizing pneumonia response measurement in HAP/VAP does not by itself define the treatment estimand ...
Coronary Artery Disease and Microvascular Dysfunction Characterized in Stabilized Sepsis Patients
A clinical study evaluation details coronary microvascular dysfunction, obstructive coronary artery disease rates, and diagnostic predictors in stabilized patients with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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