Genomic Scars May Predict Which Rectal Cancers Respond to Radioimmunotherapy
A new study finds that homologous recombination deficiency scores show a surprising non-monotonic relationship with pathological response to short-course radiotherapy ...
Tag: copy number variation
Pangenome Graphs and a Cosine Trick Let Shallow Sequencing Crack Complex Genes
A new pangenome graph tool called COSIGT uses cosine similarity to accurately genotype complex genomic loci from sequencing data as ...
Blood or skin? The starting cell may shape hidden DNA flaws in stem cell lines
A Stanford study using optical genome mapping on 73 early-passage induced pluripotent stem cell clones finds that fibroblast-derived lines carry ...
Protein Assembly, Not Abundance, Explains Why Cells Behave So Differently
A multi-omics study shows that protein complex assembly and activity states, rather than abundance alone, buffer genetic variation and drive ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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