Chemotherapy After Hormone Therapy Fails Leaves Metastatic Breast Cancer Patients With Grim Odds
A study of more than 5,000 US patients with HR-positive/HER2-negative metastatic breast cancer found median survival of only 13.5 months ...
Tag: chemotherapy
Liposomal Paclitaxel With HER-2 Blockers Shows Strong Real-World Results in Advanced Breast Cancer
A real-world study of 526 patients found that paclitaxel liposome combined with anti-HER-2 targeted therapies delivered median overall survival of ...
New 5-FU Derivative EB-18 Shows Potency Against Resistant Cancers
Researchers have engineered EB-18, a phosphonium-substituted derivative of the classic chemotherapy drug 5-fluorouracil that outperforms 5-FU and standard agents in ...
New Prediction Tool Guides Treatment Choices in Elderly Women with Bone-Spread Lung Cancer
Researchers built and validated a nomogram that predicts survival and identifies which elderly female lung cancer patients with bone metastases ...
Calcium-Rich Bone Environment Helps Osteosarcoma Cells Survive Chemotherapy
Researchers have discovered that the calcium-rich bone microenvironment drives chemotherapy tolerance in osteosarcoma through an ORAI3–Ca²⁺–NFAT4–PINK1 mitophagy axis that can ...
Chemotherapy Speeds One Aging Marker in Breast Cancer but Leaves Epigenetic Clocks Untouched
A head-to-head study of women with early breast cancer finds that T-cell p16INK4a and DNA methylation clocks are only weakly ...
ApoA2 Drives Metastasis and Drug Resistance in Liver Cancer Through HMGB1/IL-17A Signaling
New research shows that the blood lipid protein ApoA2 promotes metastasis and chemotherapy resistance in hepatocellular carcinoma by activating an ...
New 2025 Chinese Guidelines Redefine How Colorectal Cancer Liver Metastases Are Diagnosed and Treated
The 2025 Chinese guidelines consolidate two decades of evidence into an updated roadmap for diagnosing, preventing and treating colorectal cancer ...
Five-Year Data Confirm Lasting Benefit of Pembrolizumab Chemotherapy Combo in Cervical Cancer
Five-year results from the KEYNOTE-826 trial confirm that adding pembrolizumab to first-line chemotherapy delivers durable survival benefit for patients with ...
Dual PI3K/mTOR Inhibitor VDC597 Shows Promise Against Canine Lymphoma and Leukemia in Lab Studies
A dual PI3K/mTOR inhibitor, VDC597, suppresses signaling, kills canine lymphoma and leukemia cells in vitro, and synergizes with dexamethasone, according ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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