NASP Controls Histone Turnover Behind PARP Resistance
The emergence of poly(ADP-ribose) polymerase inhibitors (PARPi) as a transformative therapy for homologous recombination-deficient tumors has significantly altered the landscape ...
Tag: BRCA1 and BRCA2 mutations
Autocrine Interferon Triggers ADAR1 Synthetic Lethality in BRCA Mutants
In the relentless pursuit to understand and exploit the vulnerabilities of cancer cells, researchers have uncovered an intricate interplay between ...
UMass Chan Scientists Challenge Traditional Views on the Mechanism of Action of Anticancer Drugs
Recent groundbreaking research conducted by scientists at UMass Chan Medical School has yielded promising insights into the mechanisms underlying the ...
New Insights From Chinese Medical Journal Highlight the Anticancer Efficacy of Poly ADP-Ribose Polymerase Inhibitors
Poly(ADP-ribose) polymerase (PARP) inhibitors have emerged as a groundbreaking class of anticancer agents, particularly attractive for their mechanism of action ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Warm seawater speeding up melting of ‘Doomsday Glacier,’ scientists warn
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