Machine Learning Meets Thermal Liquid Biopsy to Spot Ovarian Cancer Before Surgery
A machine learning model combining serum thermal fingerprints from differential scanning calorimetry with clinical variables achieved an AUC of 0.85 ...
Tag: BMC Medicine
When Negative Trials Hide Real Benefits: Bayesian Probabilities Rethink Clinical Evidence
A Bayesian re-analysis of hundreds of published clinical trials shows that statistically negative studies can hide strong evidence of benefit ...
PARP Inhibitor Plus Temozolomide Shows Promise in Relapsed Small-Cell Lung Cancer Trial
A phase Ib/II trial in China found that the oral PARP inhibitor HTMC0435 combined with temozolomide produced a manageable safety ...
Low-Frequency Spinal Cord Stimulation Emerges as Top Neuromodulation Option for Neuropathic Pain
A network meta-analysis of 115 randomized controlled trials finds that low-frequency spinal cord stimulation carries the strongest evidence for treating ...
Rising CO2 and Heatwaves Together May Raise Diabetes Risk, Landmark Chinese Study Finds
A study of over 134,000 people in China finds that higher carbon dioxide concentrations and more frequent heatwaves are each ...
Healthy Habits Pay Unequal Dividends: Where You Live Shapes How Lifestyles Slow Ageing
A study of more than 155,000 adults across 32 countries finds that the healthy-ageing benefits of good lifestyles vary up ...
Kawasaki Disease Treatment Timing: Study of 6,921 Children Reveals a Surprising U-Shaped Risk
A retrospective study of 6,921 children with Kawasaki disease finds a U-shaped relationship between treatment timing and immunoglobulin resistance, while ...
Drug Safety Evidence Has a Shelf Life: Most Harm Findings Expire Within Three Years
A large retrospective cohort study of 505 meta-analyses finds that most early evidence on medication harms expires within about three ...
AI Reads Ultrasound to Sort Parotid Tumors With Striking Accuracy
A multicenter study shows a deep learning model called GobletNet can segment and classify parotid gland tumors on ultrasound with ...
Antidepressants and Breast Cancer: Landmark Analysis of Nearly Two Million Women Reveals Timing Matters
A meta-analysis of twenty-three studies covering nearly 1.83 million women finds that short-term SSRI use is associated with a modest ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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