Topoisomerase TOP2A Keeps Stem Cells Young by Guarding Lamin B1 and Heterochromatin
A new study in Aging Cell shows that the DNA-remodeling enzyme TOP2A sustains Lamin B1 expression to preserve heterochromatin, and ...
Tag: Aging
Giloy Extract Attenuates D-Galactose-Induced Aging in Mice via AMPK-SIRT1 Pathway
An ethanolic extract of Tinospora cordifolia attenuated D-galactose-induced aging in mice by restoring oxidative, inflammatory, and pro-longevity biomarkers in liver ...
Light Therapy Clears Brain Waste in Young and Middle-Aged Mice but Fails in Old Ones
A mouse study finds that photobiomodulation improves learning and amyloid beta clearance in young and middle-aged animals, but not in ...
Three Latent Classes of Physical Limitations Identified Among Older Vietnamese Adults
A study of national survey data from Vietnam identified three consistent latent classes of physical limitations among older adults characterized ...
Inflammation marker CRP/albumin ratio linked to mild cognitive impairment in older adults
A cross-sectional study of 300 adults aged 65 and older found that a higher CRP/albumin ratio was independently associated with ...
Neurons Do Not Die Alone: Why Neurodegeneration Is a Disease of the Tissue Around Them
A new PLOS Biology Editorial argues that neurodegeneration research must look beyond dying neurons to the glia, vasculature, immune signals ...
Handgrip strength predicts death more strongly in older Mexican men than women
A cohort study of 1,917 older Mexican adults found that low handgrip strength was linked to higher all-cause mortality, with ...
Exercise plus daily movement linked to lowest eight-year risk of mobility decline in Japanese cohort
An eight-year Japanese cohort study found that adults who combined habitual exercise with sufficient daily physical activity had the lowest ...
CSF GFAP Rises Sharply With Age, New Reference Limits Show
A cross-sectional study of 325 screened Danish biobank participants establishes age-specific upper reference limits for Simoa-measured CSF GFAP, which rise ...
Visuo-spatial attention shapes how reading declines in healthy aging
A study of 120 healthy older adults found that general cognitive functions mediate age-related reading decline, while visuo-spatial attention moderates ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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