Friday, September 5, 2025
Science
No Result
View All Result
  • Login
  • HOME
  • SCIENCE NEWS
  • CONTACT US
  • HOME
  • SCIENCE NEWS
  • CONTACT US
No Result
View All Result
Scienmag
No Result
View All Result
Home Science News Cancer

Study finds potential new treatment path for lasting Lyme disease symptoms

April 18, 2024
in Cancer
Reading Time: 3 mins read
0
Study finds potential new treatment path for lasting Lyme disease symptoms
66
SHARES
598
VIEWS
Share on FacebookShare on Twitter
ADVERTISEMENT

Tulane University researchers have identified a promising new approach to treating persistent neurological symptoms associated with Lyme disease, offering hope to patients who suffer from long-term effects of the bacterial infection, even after antibiotic treatment. Their results were published in Frontiers in Immunology. 

Tulane University researchers have identified a promising new approach to treating persistent neurological symptoms associated with Lyme disease, offering hope to patients who suffer from long-term effects of the bacterial infection, even after antibiotic treatment. Their results were published in Frontiers in Immunology. 

Lyme disease, caused by the bacterium Borrelia burgdorferi and transmitted through tick bites, can lead to a range of symptoms, including those affecting the central and peripheral nervous systems. While antibiotics can effectively clear the infection in most cases, a subset of patients continues to experience symptoms such as memory loss, fatigue, and pain—a condition often referred to as post-treatment Lyme disease syndrome. 

Principal investigator Geetha Parthasarathy, PhD, an assistant professor of microbiology and immunology at the Tulane National Primate Research Center, has discovered that fibroblast growth factor receptor inhibitors, a type of drug previously studied in the context of cancer, can significantly reduce inflammation and cell death in brain and nerve tissue samples infected with Borrelia burgdorferi. This discovery suggests that targeting FGFR pathways may offer an exciting new therapeutic approach to addressing persistent neuroinflammation in patients with post-treatment Lyme disease syndrome.  

“Our findings open the door to new research approaches that can help us support patients suffering from the lasting effects of Lyme disease,” Parthasarathy said. “By focusing on the underlying inflammation that contributes to these symptoms, we hope to develop treatments that can improve the quality of life for those affected by this debilitating condition.”

Researchers treated nerve tissue with live or inactivated Borrelia burgdorferi, followed by an application of FGFR inhibitors. Study results revealed a significant reduction in both inflammatory markers and of cell death. 

While further research is needed to translate these findings into clinical treatments, the study represents an important step forward in understanding and potentially managing the complex aftermath of Lyme disease.

This study was funded by the Bay Area Lyme Foundation and supported with resources from the Tulane National Primate Research Center base grant of the National Institutes of Health, P51 OD011104. 



Journal

Frontiers in Immunology

DOI

10.3389/fimmu.2024.1327416

Method of Research

Experimental study

Subject of Research

Animal tissue samples

Article Title

Fibroblast growth factor receptor inhibitors mitigate the neuropathogenicity of Borrelia burgdorferi or its remnants ex vivo

Article Publication Date

3-Apr-2024

COI Statement

The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Share26Tweet17
Previous Post

MRE 2024 Publication of Enduring Significance Awards

Next Post

Metacognitive abilities like reading the emotions and attitudes of others may be more influenced by environment than genetics

Related Posts

blank
Cancer

New Radiotheranostic Targets Discovered for Enhanced Diagnosis and Treatment of Endometrial Cancer

September 4, 2025
blank
Cancer

Identifying a Genetic Vulnerability in Synovial Sarcoma

September 4, 2025
blank
Cancer

Comprehensive Sequencing Study Reveals Minimal Connections Between Cancer and Microbiome

September 4, 2025
blank
Cancer

Dietary Changes Emerge as Potential Therapeutic Strategy for Brain Cancer

September 4, 2025
blank
Cancer

September 4, 2025: Key Research Breakthroughs from MSK

September 4, 2025
blank
Cancer

ASTRO Unveils Breakthroughs in Radiation Medicine and Cancer Research at 2025 Annual Meeting

September 4, 2025
Next Post
Metacognitive abilities like reading the emotions and attitudes of others may be more influenced by environment than genetics

Metacognitive abilities like reading the emotions and attitudes of others may be more influenced by environment than genetics

  • Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study

    Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study

    27544 shares
    Share 11014 Tweet 6884
  • University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept

    958 shares
    Share 383 Tweet 240
  • Bee body mass, pathogens and local climate influence heat tolerance

    643 shares
    Share 257 Tweet 161
  • Researchers record first-ever images and data of a shark experiencing a boat strike

    510 shares
    Share 204 Tweet 128
  • Warm seawater speeding up melting of ‘Doomsday Glacier,’ scientists warn

    313 shares
    Share 125 Tweet 78
Science

Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!

RECENT NEWS

  • Heavy Metal Pollution in Morocco’s Makhat Watershed
  • Hairy Black Holes: Scrambling Cosmic Past
  • Impact of Vegetable Waste on Labeo Rohita Growth
  • Ultra-Compact Plasmonic Nanocavity Boosts Magnetic SHG

Categories

  • Agriculture
  • Anthropology
  • Archaeology
  • Athmospheric
  • Biology
  • Blog
  • Bussines
  • Cancer
  • Chemistry
  • Climate
  • Earth Science
  • Marine
  • Mathematics
  • Medicine
  • Pediatry
  • Policy
  • Psychology & Psychiatry
  • Science Education
  • Social Science
  • Space
  • Technology and Engineering

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 5,183 other subscribers

© 2025 Scienmag - Science Magazine

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • HOME
  • SCIENCE NEWS
  • CONTACT US

© 2025 Scienmag - Science Magazine

Discover more from Science

Subscribe now to keep reading and get access to the full archive.

Continue reading