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Sex and size disparities in access to liver transplant for patients with hepatocellular carcinoma

September 4, 2024
in Biology
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About The Study: In this study, women with hepatocellular carcinoma were less likely to receive a deceased-donor liver transplant and more likely to die while wait-listed than men with hepatocellular carcinoma; these differences were largely (but not entirely) explained by sex-based differences in candidate size. For candidates listed with exception scores, additional changes to allocation policy are needed to resolve the sex disparity, including solutions to improve access to size-matched donor livers for smaller candidates. 

About The Study: In this study, women with hepatocellular carcinoma were less likely to receive a deceased-donor liver transplant and more likely to die while wait-listed than men with hepatocellular carcinoma; these differences were largely (but not entirely) explained by sex-based differences in candidate size. For candidates listed with exception scores, additional changes to allocation policy are needed to resolve the sex disparity, including solutions to improve access to size-matched donor livers for smaller candidates. 

Corresponding Author: To contact the corresponding author, Heidi Yeh, MD, email hyeh@mgh.harvard.edu.

To access the embargoed study: Visit our For The Media website at this link

(doi:10.1001/jamasurg.2024.3498)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Journal

JAMA Surgery

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