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Preoperative GLP-1 receptor agonist use and risk of postoperative respiratory complications

April 22, 2024
in Medicine
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Preoperative GLP-1 receptor agonist use and risk of postoperative respiratory complications
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About The Study: Preoperative use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in patients undergoing emergency surgery was not associated with a higher risk of postoperative respiratory complications compared with patients not using GLP-1 RAs. The results of this study suggest that liberalizing withholding guidelines for GLP-1 RAs preoperatively should be considered. 

About The Study: Preoperative use of glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in patients undergoing emergency surgery was not associated with a higher risk of postoperative respiratory complications compared with patients not using GLP-1 RAs. The results of this study suggest that liberalizing withholding guidelines for GLP-1 RAs preoperatively should be considered. 

Authors: Anjali A. Dixit, M.D., M.P.H., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link

(doi:10.1001/jama.2024.5003)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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JAMA

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