In recent years, the expansion of non-medical prescribing (NMP) has emerged as a transformative development within healthcare systems worldwide, promising to enhance service accessibility and efficiency. NMP empowers nurses, pharmacists, and allied health professionals with the authority to prescribe medications, traditionally a domain restricted to physicians. Despite its widespread adoption across various medical fields, the specific role and impact of NMP within the realm of mental health care remains insufficiently explored. A comprehensive scoping review, soon to be published in BMC Psychiatry, systematically maps the available scientific evidence on this critical topic, revealing new insights into how non-medical prescribers shape mental health treatment landscapes.
The scoping review synthesizes research conducted over two decades, spanning from 2003 to mid-2024, reflecting a growing interest in the deployment of NMP in managing mental illness and dementia within community settings. Drawing from an exhaustive search of five electronic databases and additional reference checks, the authors distilled more than twenty-two thousand records into 63 pertinent studies. These studies collectively illuminate the nature, impact, and implementation challenges of NMP services directed at psychiatric populations, underscoring the diverse applications and outcomes of non-medical prescription in real-world clinical practice.
One of the major findings centers on understanding the professional composition and prescribing behaviors of NMP practitioners. Nurses dominate the research focus, representing nearly 70% of the examined studies, followed by pharmacists, who account for around 25%. Interestingly, interdisciplinary models involving both nurses and pharmacists appear underrepresented, suggesting a potential area for expansion and evaluation. In terms of pharmacological management, antidepressants emerge as the most frequently prescribed medications by non-medical prescribers in both the United Kingdom and the United States, providing a quantitative glimpse into the clinical decision-making patterns within these healthcare systems.
While the breadth of descriptive data regarding service models and prescribing patterns is extensive, the review highlights a critical gap in rigorous outcome evaluation. Only a minority of studies measure patient health outcomes quantitatively, a limitation that tempers definitive conclusions about the clinical efficacy of NMP in mental health care. Nevertheless, where examined, the outcomes suggest positive patient management, with both nurse and pharmacist prescribers demonstrating comparable success in effectively treating mental health conditions based on clinical indicators. This tentative evidence affirms NMP’s potential but simultaneously calls for more robust, data-driven research to validate these preliminary findings.
Implementation challenges form a salient theme within the literature, with geographic variations highlighting context-specific barriers. In the United Kingdom, training-related obstacles frequently impede the scale and scope of non-medical prescribing services, reflecting gaps in professional development and credentialing pathways. Conversely, economic issues are more pronounced in the United States, where financial constraints limit service delivery and expansion. These differences emphasize the complexity of embedding NMP within diverse health systems and the necessity for tailored strategies addressing training infrastructure and funding mechanisms.
From a technical standpoint, the review underscores the sophisticated integration of NMP within multidisciplinary mental health teams. Non-medical prescribers often operate in community-based environments, engaging closely with patients to monitor treatment adherence, medication side effects, and symptomatology. The autonomous or collaborative prescribing roles assumed by nurses and pharmacists facilitate streamlined care pathways, potentially reducing wait times and alleviating burdens on psychiatrists. These operational efficiencies exemplify how NMP can innovate traditional mental health care delivery models, merging clinical expertise with enhanced patient-centered approaches.
Despite the encouraging indications of NMP’s contribution to mental health management, this field confronts ongoing workforce challenges, notably the persistent shortages of qualified mental health professionals. As the prevalence of mental illness continues to rise globally, healthcare systems face mounting pressure to innovate care models that balance demand and resource constraints. Non-medical prescribing, particularly when extended to pharmacists and allied health professionals, offers a viable pathway to expand access without compromising quality. However, realizing this potential hinges on strategic investment in training, regulatory frameworks, and outcome research.
Another critical dimension of the review is its call to diversify the scope of research beyond nursing models. Pharmacist-led prescribing services, while less studied, present unique opportunities due to pharmacists’ specialized expertise in pharmacotherapy and medication management. Evaluating their role could reveal insights into optimizing medication regimens, mitigating drug interactions, and enhancing patient safety. Moreover, the inclusion of other allied health professionals in NMP frameworks could further amplify the multidisciplinary approach necessary for holistic mental health care.
Technological advancements are poised to strengthen NMP implementation in mental health settings. Electronic prescribing systems, telehealth platforms, and integrated patient records enable non-medical prescribers to access real-time clinical data, facilitate specialist consultations, and monitor treatment courses dynamically. These tools improve decision-making accuracy and support the scalability of NMP services in both urban and rural communities. Future research should investigate how digital health technologies intersect with NMP to maximize therapeutic outcomes and service efficiency.
Policy implications from this review are substantial. Health authorities and professional bodies must consider how to adapt regulatory standards to encompass evolving NMP roles while ensuring rigorous competency assessment and ethical prescribing practices. Funding models should incentivize training programs and service delivery innovations that enable non-medical prescribers to practice at the top of their licenses. Furthermore, the integration of NMP into mental health strategies must be sensitive to local healthcare landscapes, incorporating stakeholder input, patient preferences, and evidence-based protocols.
In conclusion, the scoping review published by Alsaeed, Hall, and Keers represents a seminal step in elucidating the contributions and limitations of non-medical prescribing within mental health care. It reveals a landscape marked by promising developments juxtaposed with significant research gaps, particularly in quantifying patient outcomes and exploring underrepresented professional groups. As mental health demands intensify globally, expanding the role of non-medical prescribers offers a practical and innovative avenue to enhance care delivery. Embracing this potential requires a concerted effort in research, education, policy, and technology integration to ensure that NMP services are effective, sustainable, and patient-centered.
The future of mental health prescribing is undoubtedly multidisciplinary and collaborative. By fostering robust evidence and sharing international best practices, the healthcare community can leverage the skills of nurses, pharmacists, and allied health professionals to transform mental health care accessibility and quality. This review serves as a foundational reference point for policymakers, clinicians, and researchers aiming to harness the full capabilities of non-medical prescribing in addressing one of the most pressing health challenges of our time.
Subject of Research: Non-medical prescribing (NMP) for patients with mental illness and dementia, focusing on service nature, impact, and implementation in community settings.
Article Title: Exploring non-medical prescribing for patients with mental illness: a scoping review
Article References:
Alsaeed, B.A., Hall, J. & Keers, R.N. Exploring non-medical prescribing for patients with mental illness: a scoping review. BMC Psychiatry 25, 504 (2025). https://doi.org/10.1186/s12888-025-06938-6
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