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Medicare Cost Impact of Semaglutide Under Voluntary Price Agreements

April 2, 2026
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About The Study: This analysis suggests that the lower semaglutide price of $245 per month established under the Centers for Medicare & Medicaid Services (CMS) Innovation Center demonstration project—the Better Approaches to Lifestyle and Nutrition for Comprehensive Health (BALANCE) model could generate savings that would offset the cost of treating an additional 550,000 to 3.6 million Medicare beneficiaries eligible for expanded obesity-indication coverage, depending on assumptions about baseline use and further price reductions.

Corresponding Author: To contact the corresponding author, Stacie B. Dusetzina, PhD, email s.dusetzina@vanderbilt.edu.

To access the embargoed study: Visit our For The Media website at this link

(doi:10.1001/jama.2026.2615)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time 



Journal

JAMA

Media Contact

JAMA Network Media Relations

JAMA Network

mediarelations@jamanetwork.org

Journal
JAMA

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JAMA

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  • /Life sciences/Biochemistry/Biomolecules/Agonists

  • /Health and medicine/Diseases and disorders/Immune disorders/Autoimmune disorders/Diabetes/Type 2 diabetes

  • /Life sciences/Organismal biology/Morphology/Body weight/Weight loss

  • /Social sciences/Economics/Finance/Insurance/Health insurance

  • /Life sciences/Biochemistry/Protein functions/Protein activation/Receptor activation

  • /Applied sciences and engineering/Information science/Information processing/Data analysis

  • /Health and medicine/Diseases and disorders/Metabolic disorders/Obesity

  • /Social sciences/Political science/Government/Public policy/Science policy/Research management/Research funding/Cost effectiveness

  • /Life sciences/Physiology/Nutritional physiology/Nutrition

  • /Health and medicine/Human health

  • /Social sciences/Economics/Medical economics

  • /Social sciences/Economics/Medical economics/Drug costs

bu içeriği en az 2000 kelime olacak şekilde ve alt başlıklar ve madde içermiyecek şekilde ünlü bir science magazine için İngilizce olarak yeniden yaz. Teknik açıklamalar içersin ve viral olacak şekilde İngilizce yaz. Haber dışında başka bir şey içermesin. Haber içerisinde en az 12 paragraf ve her bir paragrafta da en az 50 kelime olsun. Cevapta sadece haber olsun. Ayrıca haberi yazdıktan sonra içerikten yararlanarak aşağıdaki başlıkların bilgisi var ise haberin altında doldur. Eğer yoksa bilgisi ilgili kısmı yazma.:
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Keywords

Tags: BALANCE model obesity treatmentCMS voluntary price agreementshealthcare cost offset obesity drugsMedicare beneficiaries obesity treatmentMedicare cost impact of semaglutideMedicare obesity coverage expansionobesity-indication drug coverage Medicarepharmaceutical price demonstration projectssemaglutide cost savings analysissemaglutide monthly cost studysemaglutide price reduction effectssemaglutide pricing under CMS Innovation Center
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