Pressure injuries, commonly known as bedsores, represent a significant healthcare challenge, particularly for the elderly population in inpatient settings. This demographic is often more vulnerable to the development of such injuries due to a multitude of factors, including decreased mobility and skin integrity. In recent years, researchers have increasingly focused on uncovering the intricate risk factors that contribute to the onset of pressure injuries, culminating in a comprehensive systematic review and meta-analysis that sheds light on this pressing issue.
This systematic review, led by a team of researchers including Wu, Cheng, and Cao, examines existing studies to identify the predominant risk factors associated with pressure injuries in elderly inpatients. The synthesis of such data not only highlights the critical need for enhanced preventative measures but also serves to inform clinical protocols to protect vulnerable patients from avoidable harm. The findings are expected to resonate widely within the medical community as they underscore the importance of proactive interventions.
Age-related physiological changes dramatically influence the skin’s resilience among elderly patients. With aging comes a natural decline in the dermal thickness and elasticity, rendering skin more susceptible to damage. Furthermore, the elderly often experience comorbidities such as diabetes, which can impede wound healing and exacerbate skin integrity issues. As healthcare systems grapple with these complexities, understanding the interaction between these inherent aging factors and environmental pressures is crucial.
Mobility levels represent another significant contributor to pressure injuries. Elderly inpatients frequently face limited mobility due to pain, cognitive impairments, or medical conditions, constituting a major risk factor. The pressure and friction exerted on specific body parts, especially in those confined to beds or wheelchairs, often lead to the formation of ulcers. As highlighted in the review, implementing regular repositioning schedules can mitigate these risks and promote better outcomes, yet compliance can be challenging in busy clinical settings.
Nutrition also plays an integral role in skin health and wound healing. Under-nutrition or malnutrition can severely compromise skin integrity and immune function, making the elderly more vulnerable to pressure injuries. The review emphasizes that adequate protein intake and balanced nutrition are essential in fortifying skin resilience. However, challenges remain in ensuring that elderly patients receive sufficient nourishment during their hospital stay, especially if they have difficulty swallowing or digesting food.
Moisture, whether from incontinence or excessive sweating, significantly heightens the risk of pressure injuries as well. The presence of moisture can weaken the skin barrier and increase friction, thereby creating an enabling environment for skin breakdown. The systematic review underscores the importance of effective moisture management strategies, such as the use of barrier creams and moisture-wicking materials, to protect sensitive skin.
Moreover, the psychological aspect of patient care cannot be overlooked. Cognitive impairments associated with aging, such as dementia, pose additional challenges in preventing pressure injuries. Patients who are unaware of their condition or unable to communicate their discomfort may remain in one position for extended periods, increasing their risk. This necessitates a more holistic approach to care that incorporates cognitive assessments and tailored interventions to address the unique needs of these patients.
Ethnicity and cultural factors also emerge as crucial variables influencing the prevalence of pressure injuries among elderly inpatients. Disparities in access to healthcare resources based on socioeconomic and racial backgrounds can contribute to variations in the occurrence of these injuries. The review highlights a critical need for healthcare providers to recognize these disparities and work toward creating equitable care plans that account for individual risk factors inherent in different populations.
Technological advancements are enhancing assessments and interventions aimed at pressure injury prevention. Tools such as pressure mapping and digital monitoring systems offer clinicians real-time data on patient positioning and skin health, enabling targeted interventions. The systematic review advocates for the integration of such technologies into daily practice to bolster the prevention strategies that safeguard at-risk patients.
Furthermore, continuous education and training programs for healthcare professionals about the latest evidence-based practices for preventing pressure injuries are vital. The review advocates for institutional commitment to ongoing professional development, ensuring that care teams remain well-informed and prepared to implement effective prevention strategies. Knowledge dissemination is key to fostering a culture of awareness and accountability in healthcare settings.
Future research directions should center on exploring innovative interventions and technologies that can further reduce the prevalence of pressure injuries. Investigative efforts that focus on individualized risk assessments and tailored preventive interventions will likely yield significant improvements in patient outcomes. Collaborative studies across multiple institutions can also help in understanding diverse patient populations better and identifying specific needs that may not be universally applicable.
In conclusion, the systematic review and meta-analysis conducted by Wu and colleagues underscore a diverse array of risk factors associated with pressure injuries in elderly inpatients. By highlighting the intricate interplay between physiological, environmental, nutritional, and psychological factors, this seminal work emphasizes the urgent need for concentrated efforts to enhance prevention strategies and protect this vulnerable population. Through ongoing research, education, and the integration of technology, the medical community can aspire to drastically reduce the incidence of pressure injuries and promote better, safer care for elderly patients in hospitals.
As healthcare professionals rally to implement strategies informed by this review, the hope is to see a significant decline in pressure injury rates, ultimately enhancing the quality of life for elderly patients and ensuring their dignity during hospital stays. The findings serve as a call to action, advocating for systemic changes that prioritize patient safety and well-being among elderly inpatients, ensuring that pressure injuries are no longer seen as an inevitable consequence of aging or hospitalization but as a preventable concern.
Subject of Research: Risk factors of pressure injury in elderly inpatients
Article Title: Risk factors of pressure injury in elderly inpatients: a systematic review and meta-analysis
Article References:
Wu, Q., Cheng, N., Cao, F. et al. Risk factors of pressure injury in elderly inpatients: a systematic review and meta-analysis.
BMC Geriatr 25, 874 (2025). https://doi.org/10.1186/s12877-025-06517-0
Image Credits: AI Generated
DOI: https://doi.org/10.1186/s12877-025-06517-0
Keywords: Pressure injuries, elderly inpatients, prevention strategies, healthcare challenges, systematic review.

