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Home Science News Psychology & Psychiatry

DASS-21 Validated in Honduran and Colombian Students

November 30, 2025
in Psychology & Psychiatry
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In recent years, the intricate landscape of mental health assessment has witnessed significant advancements, particularly with efforts to refine the tools employed for measuring psychological distress in diverse populations. A groundbreaking study authored by Castillo-Díaz and Periañez, published in BMC Psychology in 2025, offers a comprehensive evaluation of the Depression, Anxiety, and Stress Scale-21 (DASS-21) as applied to university students in Honduras and Colombia. This investigation delves into crucial psychometric properties including dimensionality, reliability, invariance, and item-level analysis, yielding insights that not only enhance our understanding of the tool’s applicability but also extend its relevance across cultural contexts.

The DASS-21, a widely utilized self-report instrument, has become a staple in both clinical and research settings due to its concise yet robust capacity to measure three related but distinct constructs: depression, anxiety, and stress. Nevertheless, despite its global adoption, questions persist regarding its factorial structure and measurement consistency when deployed across culturally diverse groups, especially in Latin American populations where mental health research is still burgeoning. Castillo-Díaz and Periañez address this gap by examining whether the scale’s theoretical underpinnings hold true within Honduran and Colombian university cohorts, which are characterized by unique social, economic, and cultural stressors.

At the heart of their analysis lies the issue of dimensionality, which pertains to whether the DASS-21 successfully captures the three separate dimensions it intends to measure or if a different, perhaps more unified, factor structure emerges within these populations. Utilizing rigorous statistical modeling techniques, including confirmatory factor analysis (CFA), the authors test competing models ranging from a three-factor structure to a bifactor solution and even a unidimensional framework. Their data compellingly demonstrate that the original three-factor model is largely upheld, affirming the scale’s conceptual delineation of depression, anxiety, and stress in the targeted student groups. This confirmation is pivotal, as dimensional integrity underpins the validity of any psychological instrument.

Reliability, another cornerstone of psychometric evaluation, is scrutinized through multiple indices such as Cronbach’s alpha and McDonald’s omega coefficients. High internal consistency coefficients observed across all subscales reinforce the reliability of the DASS-21 within these Latin American samples. This finding assures clinicians and researchers alike that the tool produces stable and replicable scores, an essential prerequisite when tracking mental health symptoms over time or assessing intervention outcomes. Particularly noteworthy is the maintenance of reliability across two distinct national contexts, suggesting both robustness and generalizability.

Importantly, the study transcends traditional psychometric appraisal by integrating tests of measurement invariance—an advanced methodological approach that examines whether the instrument functions equivalently across groups. Through a multi-group CFA framework, Castillo-Díaz and Periañez investigate configural, metric, scalar, and residual invariance between Honduran and Colombian students. Their results affirm strict invariance for most parameters, bolstering the premise that comparisons of depression, anxiety, and stress scores between these populations reflect true differences rather than measurement artifacts. This insight is invaluable for epidemiological tracking and the development of regionally sensitive mental health policies.

Delving deeper, the authors undertake a meticulous item analysis to identify the performance characteristics of individual items within the DASS-21. Such granular scrutiny provides clarity on whether specific items align with their intended constructs and whether any exhibit bias or poor discrimination. Item response theory (IRT) methods illuminate the strength and precision of each question, uncovering subtle nuances in how students interpret and respond to scale statements. This level of detail facilitates potential refinements to the scale, ensuring it remains both psychometrically sound and culturally resonant.

Contextualizing the significance of this research demands recognition of the escalating mental health challenges facing university students globally. The transition to higher education is often fraught with academic pressures, social adjustments, and emerging identity issues, all of which can exacerbate symptoms of depression, anxiety, and stress. Latin American students confront additional layers of complexity, including economic instability and limited access to mental health services. Accordingly, reliable and valid measurement tools like the Spanish-language DASS-21 are indispensable for early detection and intervention efforts—tools that this study robustly validates.

The authors also engage with broader theoretical implications, especially surrounding the multicultural applicability of psychological constructs. By confirming the DASS-21’s factorial structure and invariance in Honduran and Colombian contexts, Castillo-Díaz and Periañez contribute empirical weight to cross-cultural psychology debates. Their findings underscore that constructs of depression, anxiety, and stress retain conceptual consistency yet highlight the necessity of contextual sensitivity when interpreting symptom expression and severities. Such insights challenge researchers to balance universality with cultural specificity in mental health research paradigms.

Moreover, the methodological rigor demonstrated throughout the study exemplifies best practices in psychometrics. The sequential and comprehensive testing strategy—progressing from factor structure exploration to reliability estimation, and finally cross-group invariance testing—serves as a model for future validation studies. The application of both classical test theory and modern approaches like IRT underscores the sophistication of contemporary scale analyses, enabling researchers to uncover multi-level psychometric properties that simpler methods might overlook.

Beyond academia, the practical implications of this research are profound. Universities, counselors, and public health officials in Latin America can leverage the validated DASS-21 to monitor student mental health burdens with confidence, supporting data-driven program development. Screening and assessment efforts aided by this tool can facilitate timely psychological support, potentially mitigating the progression of mental health disorders. As mental health awareness campaigns permeate educational institutions, having a culturally adapted and psychometrically validated measure is crucial for meaningful impact.

Additionally, this study’s dual-country design warrants commendation, providing comparative data that enrich understanding of regional mental health dynamics in Latin America. The confirmation of measurement invariance indicates that interventions and policies can be crafted with a regional perspective, fostering collaborative frameworks that transcend national boundaries. Such cooperation is vital in addressing shared societal challenges, including stigma reduction and resource allocation.

Furthermore, the research prompts reflection on translation and adaptation processes in scale development. The linguistic and cultural tailoring of the DASS-21 to Spanish-speaking populations is validated through empirical evidence, affirming translation fidelity and cultural appropriateness. This is a non-trivial achievement, considering that direct translations often fail to capture nuanced emotional experiences. Hence, Castillo-Díaz and Periañez’s work validates not only the psychometrics but also the cultural translation efforts that underpin the scale’s deployment.

In the wider scope of mental health measurement, this study highlights the ongoing need for localized validation efforts. Even widely endorsed instruments require periodic re-examination to confirm their relevance in evolving sociocultural milieus. As new generations of students emerge amidst shifting geopolitical and technological landscapes, their psychological experiences may differ from previous cohorts, necessitating continuous psychometric vigilance.

Importantly, this research arrives at a time marked by growing recognition of psychological distress in lower- and middle-income countries, where mental health infrastructure often lags behind need. The ability to assess symptoms reliably is a foundational step toward equitable mental health care. Castillo-Díaz and Periañez provide a template for other researchers worldwide seeking to validate instruments across diverse populations, ultimately promoting global mental health equity.

In conclusion, the comprehensive psychometric evaluation of the DASS-21 conducted by Castillo-Díaz and Periañez represents a milestone in Latin American mental health research. Their meticulous examination of dimensionality, reliability, invariance, and item functioning empowers both scientific inquiry and practical applications within university settings. As mental health challenges persist globally, such robust validation studies are indispensable in ensuring that measurement tools accurately capture the multifaceted experiences of individuals across cultures and countries. This study not only strengthens confidence in the DASS-21 but also sets a high standard for future psychometric research endeavors.


Subject of Research: Psychometric validation of the Depression, Anxiety, and Stress Scale-21 (DASS-21) in Latin American university students.

Article Title: Dimensionality, reliability, invariance, and item analysis of the depression, anxiety, and stress scale-21 (DASS-21) in Honduran and Colombian university students.

Article References:
Castillo-Díaz, M.A., Periañez, C.A.H. Dimensionality, reliability, invariance, and item analysis of the depression, anxiety, and stress scale-21 (DASS-21) in Honduran and Colombian university students. BMC Psychol (2025). https://doi.org/10.1186/s40359-025-03742-5

Image Credits: AI Generated

Tags: Castillo-Díaz and Periañez researchcultural context of DASS-21DASS-21 validationdepression anxiety stress scaleHonduras and Colombia mental health studyitem-level analysis in mental healthLatin American mental health researchmental health assessment toolspsychological distress measurementpsychometric properties of DASS-21reliability and invariance in psychologyuniversity students mental health
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