Medicine
Molecular Exchange Controls Gene Regulation Complexes, Study Finds
Gene regulation is often portrayed as the work of stable molecular machines: large complexes assembled from precisely arranged parts, operating...
New obesity classification may improve treatment decisions
Obesity may need to be defined less by a person’s metabolic test results and more by whether excess body fat...
Representations of the intrinsic value of information in mouse orbitofrontal cortex
Bussell, J.J., Badman, R.P., Márton, D. et al. Representations of the intrinsic value of information in mouse orbitofrontal cortex. Nat...
Ferroptotic propagation: from single-cell execution to tissue-scale death programs
Tang, D., Kang, R. & Kroemer, G. Ferroptotic propagation: from single-cell execution to tissue-scale death programs. Cell Res (2026). https://doi.org/10.1038/s41422-026-01283-z...
Residential proximity to major roadways and prevalent diabetes in older adults: a cross-sectional study based on CLHLS
Li, Y., Feng, S., Liu, H. et al. Residential proximity to major roadways and prevalent diabetes in older adults: a...
Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments
Leng, F. Overestimations in the cyclization efficiency of small, restriction enzyme-digested DNA fragments. Nat Protoc (2026). https://doi.org/10.1038/s41596-026-01423-0 https://doi.org/10.1038/s41596-026-01423-0
Sulfated polysaccharides target RANK Lys97 to inhibit osteoclast differentiation and reverse osteoporosis
Current osteoporosis treatments fail to balance bone resorption and formation. Here we show that engineered 2-N,6-O-sulfated chitosan (26SCS), a synthetic...
Regulation of RNA transcript elongation in metazoans and its relevance to disease
Our understanding of transcript elongation by metazoan RNA polymerase II (Pol II) has grown notably in recent years. Advances in...
Expanding the repertoire of chemically induced covalent neoantigens
The ubiquitin–proteasome system generates peptide fragments that are displayed on class I major histocompatibility complex molecules. Hapten-modified peptides, or covalent...
Deadly brain tumors show vulnerability to new sound wave approach
In a promising sign for the potential of focused sound waves to improve care for brain tumors, UVA Health researchers...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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