Cancer
Bile Sequencing Turns Discarded Fluid Into Early Cancer Clues
Ultra-low-pass whole-genome sequencing of cell-free DNA in bile collected during routine ERCP detected pancreatobiliary cancers with high specificity, identified the...
When Cancer Treatment Consumes Life: Lymphoma Patients Reveal the Hidden Burden of Time Toxicity
A qualitative study of young and middle-aged lymphoma patients in China reveals how the cumulative time demands of cancer treatment...
Simple Blood Test Ratio Predicts Survival in Hodgkin Lymphoma Patients on Immunotherapy
A new study finds that an elevated platelet-to-lymphocyte ratio from a routine blood count strongly predicts poorer survival in relapsed...
Circular RNA circLPAR3 blocks ferroptosis to fuel chemotherapy resistance in prostate cancer
Researchers at Nanjing Medical University report that the m6A-stabilized circular RNA circLPAR3 suppresses ferroptosis through the PCBP2/CHAC1 axis, driving docetaxel...
Why Head and Neck Cancer Rehab Trials Must Stratify for Lymphoedema
A new correspondence in Supportive Care in Cancer argues that head and neck cancer rehabilitation trials must stratify participants by...
Two Approved Companion Diagnostics Validate Pembrolizumab Eligibility Across dMMR/MSI-H Tumors
Bridging studies confirm that the Ventana MMR RxDx Panel and FoundationOne CDx reliably identify dMMR/MSI-H tumor patients likely to respond...
Gut Microbiome Signatures Distinguish Five Cancer Types and Early-Onset Disease
A Mayo Clinic analysis of 1,364 cancer patients links distinct gut microbiome patterns to five cancer groups, early-onset colorectal and...
Self-Acupressure Eases Fatigue, Sleep Problems and Depression in Breast Cancer Survivors
A phase III randomised controlled trial shows that daily self-acupressure significantly and durably reduces the combined burden of fatigue, sleep...
Beyond the On-Off Switch: Chemical Tags on KRAS Reshape Cancer Drug Design
A new review in Advanced Cancer Research details how post-translational modifications regulate KRAS localization, activity, stability, and degradation, opening fresh...
Ribosome-Building Enzyme DIMT1 Emerges as a Pan-Cancer Biomarker and Gastric Cancer Drug Target
A comprehensive pan-cancer study identifies the ribosome biogenesis enzyme DIMT1 as a prognostic and immune-associated biomarker whose depletion suppresses gastric...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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