Cancer
Tumor-Dwelling Microbial Ecosystems Open New Frontiers in Cancer Treatment
Cancer research is entering an era in which tumors are no longer viewed as isolated masses of abnormal human cells....
Uneven mitochondrial calcium regulator distribution shapes compartment-specific function and neuronal development
A new study has identified an important spatial principle governing how mitochondria support developing neurons: the machinery that controls mitochondrial...
Blocking MDA-9 slows head and neck tumors and overcomes treatment resistance
Head and neck squamous cell carcinoma (HNSCC) is among the world’s most challenging cancers, accounting for approximately 90% of malignancies...
AI-designed first-in-class small-molecule inhibitor shows preclinical promise against pancreatic cancer
Jacksonville, Fla. — Mayo Clinic researchers have used artificial intelligence to identify an experimental small-molecule drug that targets a protein...
HKUMed research with Hong Kong Genome Institute uncovers new glioblastoma treatment targets
Glioblastoma, the most common and aggressive primary brain cancer in adults, has yielded thousands of previously hidden genetic clues in...
Macrophage-to-myofibroblast transition-derived itaconate drives lung cancer bone metastasis via HSPA8
Lung cancer’s spread to bone is one of the most destructive stages of the disease, often causing severe pain, fractures,...
Cold Spring Harbor, Northwell Health lead development of 150+ cancer treatment models
A decade-long international effort has produced the largest publicly available collection of patient-derived cancer organoids to date, giving researchers a...
Study reveals HHV-8-driven immune regulation in HIV-associated and classic Kaposi sarcoma
Kaposi sarcoma is not simply a tumour made of abnormal blood vessels. It is a complex tissue ecosystem in which...
TMEM135 Deficiency Prevents Intestinal Fat Buildup Through ELOVL6-Driven PPARα Lipid Oxidation
A molecular switch that helps the intestine manage incoming fat may have been identified in an unexpected place: the activity...
Experimental drug weaponizes cancer’s sugar addiction against tumors
Cancer cells are often described as metabolic opportunists, consuming extraordinary amounts of glucose to sustain rapid growth. A new experimental...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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