BAG3-HSP70 Autophagy Axis Emerges as Contested Target in Leukemia
A rigorous new review finds that the BAG3-HSP70 autophagy axis is prognostically relevant and pharmacologically tractable in acute myeloid leukemia,...
Ultrasound Misses Nearly a Third of Recurrent Thyroid Cancer Nodes in the Neck
A new study quantifies how ultrasound performance for detecting recurrent papillary thyroid carcinoma varies dramatically across neck levels, with sensitivity...
TRIP13 shields a key metabolic enzyme from destruction, helping colorectal cancer adapt and resist chemotherapy
TRIP13 protects LDHA from FBXW7-mediated degradation, sustaining a lactate-driven antioxidant program that helps colorectal cancer cells adapt to hypoxia and...
Design and optimization of a multi-band spiral antenna for frequency-dependent hyperthermia heating in head and neck cancer treatment
Engineers in India have built a single spiral antenna that can heat tumors at three different depths inside the head...
AI Learns Cervical Cancer’s Signature to Stay Sharp Across Hospitals
A new iScience study introduces CSCC-PAG, a deep learning framework that combines domain-specific pre-training with self-supervised domain adaptation to improve...
Tiny Droplets Inside Cells Could Decide Whether Cancer Therapy Works
A new review in Molecular Cancer synthesizes how liquid-liquid phase separation shapes radiosensitivity, immune evasion, and treatment resistance in cancer.
MRI Heterogeneity Map Predicts Brain Metastasis Progression on EGFR Drugs
For patients with EGFR-mutant lung adenocarcinoma whose cancer has already spread to the brain, third-generation EGFR-TKI drugs such as osimertinib...
Fibroblast collagen signal drives gut scarring and cancer in inflammatory bowel disease
A single-nuclei study reveals how CXCL14+ fibroblasts and SPP1+ macrophages form a collagen IV-driven feedback loop that promotes fibrosis and...
ENO3 Emerges as a Lactate-Linked Biomarker in Colorectal Cancer Metastasis
Integrated transcriptomic analysis of TCGA and GEO datasets identifies a six-gene lactate metabolism signature and nominates ENO3 as a prognosis-associated...
Brain Wiring Shifts Seen in Lung Cancer Patients With Depressive Symptoms
A resting-state fMRI study of 75 lung cancer patients in China found that those with comorbid depressive symptoms showed altered...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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