Virtual Tumors Point to New Drug Combinations for Hard-to-Treat Lung Cancer Mutations
A new quantitative systems pharmacology model spanning all three classes of BRAF-mutant lung cancer predicts that MEK-ERK inhibitor combinations can...
New AI Model Decodes the Signals That Guide Immune Cells Into Tumors
Researchers at MD Anderson developed an AI tool called SPACER that decodes the spatial signals attracting or repelling immune cells...
The Methylation Test That Decides Brain Cancer Treatment Faces a Reckoning
A new Mayo Clinic review in the Journal of Neuro-Oncology examines how MGMT promoter methylation guides brain tumor treatment, why...
Cancer Gene Mutations Awaken the Immune System in Early Oral Cancer
Researchers at Tokushima University found that combined TP53 and CDKN2A mutations activate cGAS–STING-mediated antitumor immunity, delaying progression to invasive oral...
Cancer Patients in Rural South Africa Carry a Heavy Burden of Fear, Pain and Poverty
A survey of 207 oncology patients in rural Limpopo Province reveals near-universal pain, fear of death and financial hardship, prompting...
When Tumors Hide Their Flags, Natural Killer Cells May Take Over Against Colorectal Cancer
Two patients with microsatellite-unstable metastatic colorectal cancer and markedly reduced HLA-I expression achieved durable responses to pembrolizumab, suggesting that NK...
Inside the Integrative Oncology Clinic: Who Seeks Complementary Cancer Care and What They Receive
A prospective French study of fifty patients at the Léon Bérard Cancer Center reveals who attends integrative oncology consultations, what...
Cholesterol Plummets in Oral Cancer Patients, Huge Meta-Analysis Finds
A new meta-analysis of 25 studies finds that oral cancer patients show significantly lower total cholesterol, triglycerides, HDL, LDL, and...
Tiny Antennae on Bile Duct Cells Emerge as Master Sensors of Liver Health and Disease
A new review in Nature Reviews Gastroenterology & Hepatology explains how cholangiocyte primary cilia sense bile flow, chemistry and tonicity...
Cancer Patients Carry Heavier Depression and Insomnia Burden Than Caregivers, Landmark Study Finds
A multicenter Chinese study of over 17,000 cancer patients and caregivers found patients suffer more depression, insomnia, and poorer quality...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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