Acute Myeloid Leukemia Reported 32 Months After Icotinib Therapy for EGFR-Mutated Lung Cancer
A case report and literature review describe acute myeloid leukemia developing 32 months into icotinib therapy for EGFR-mutated lung cancer,...
HDAC Inhibitor Plus Cisplatin Stabilizes Advanced Adenoid Cystic Carcinoma
Adenoid cystic carcinoma (ACC) is a rare malignancy of the salivary glands that typically follows an indolent yet persistent clinical...
STTARRS protocol plans telehealth prehabilitation trial before major cancer surgery
The STTARRS protocol plans a nine-hospital Australian randomised trial of telehealth prehabilitation in 480 adults awaiting major cancer surgery, with...
Molecular glue RPT04402 stabilizes tumor-suppressing PP2A protein in lung and uterine cancer studies
University of Michigan researchers report that the molecular glue RPT04402 stabilizes the trimeric tumor suppressor PP2A, shrinking KRAS-mutant lung tumors...
Transformer AI Model Predicts Survival in Rare Lung Neuroendocrine Cancers
A two-center retrospective cohort study of 823 surgically resected pulmonary neuroendocrine carcinoma patients found that a Transformer-based AI model achieved...
Underweight Outweighs Obesity in Gastrointestinal Cancer Death Risk in Type 2 Diabetes
A nationwide South Korean cohort of more than 2.5 million adults with type 2 diabetes found a reverse J-shaped association...
Checkpoint inhibitors linked to longer unadjusted progression-free survival in advanced thoracic tumors
A single-center cohort study linked checkpoint inhibitor-containing therapy with longer unadjusted progression-free survival in advanced SMARCA4-deficient thoracic tumors, but adjusted...
Long-Read DNA Sequencing Uncovers Hidden Cancer Drivers Missed by Standard Tests
University of Michigan researchers used long-read nanopore sequencing to resolve hidden cancer-driving alterations in tumors and to trace the origin...
Research report: Clinicopathological and molecular correlates of micropapillary/solid and lepidic patterns in lung adenocarcinoma
A retrospective study of 73 Chinese patients links micropapillary/solid and lepidic components in invasive non-mucinous lung adenocarcinoma with distinct clinical,...
Child recovers after probable blinatumomab lung injury and dose-escalation rechallenge
A case report describes a child with B-ALL who recovered from probable blinatumomab-associated lung injury and completed a monitored, dose-escalated...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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