A new ontology-guided FAIR resource called MAOMAO harmonizes peptide toxicity annotations from 56 sources into a unified, evidence-aware dataset spanning...

For decades, the idea of swallowing a peptide drug instead of injecting it has been one of drug delivery's most...

Biologic drugs have rewritten the treatment playbook for chronic and life-threatening disease, yet nearly all of them still reach patients...

The burden of protozoan disease is not evenly distributed across the globe, and this asymmetry shapes nearly every aspect of...

A systematic review of 25 studies finds that methadone maintenance therapy is consistently linked to QTc interval prolongation, with dose,...

A new Frontiers perspective chronicles how Professor Kelly Chibale built Africa's first fully integrated drug discovery centre at the University...

Indian researchers have developed metronidazole-loaded Carbopol 940 nanogels whose optimized formulation achieves 143.4 nm particles, near-complete drug release within eight...

The biopharmaceutical classification framework provides useful context for interpreting the permeability results reported in this study. Compounds with apparent permeability...

An international expert panel has ratified 26 standardised evaluation rules for peptide-target interaction prediction through a three-round eDelphi consensus, aiming...

A new review maps quantum algorithms onto every stage of drug discovery, quantifying the enormous hardware gap between today's noisy...