Variant effect prediction has entered a new phase, but one of biology’s largest blind spots remains stubbornly difficult to resolve....

A new genetic study is bringing the brain’s movement-control circuitry into sharper focus, suggesting that a person’s risk of developing...

A new study reports a step toward treating mammalian gene regulation as an engineering problem: rather than searching through the...

A single-cell transcriptomic study of the orange-spotted grouper, Epinephelus coioides, is offering an unprecedented view of how a fish gonad...

Freshwater ecosystems are home to an extraordinary fraction of Earth’s microbial diversity, yet many of the bacteria inhabiting rivers, lakes...

A gene therapy designed to replace a damaged or missing copy of the alpha protein kinase 3 gene has restored...

A new study in budding yeast suggests that one of biology’s most fundamental processes—cell growth—may be governed by a remarkably...

A new study is reshaping the way scientists understand how transcription factors find their targets inside the crowded genome. Researchers...

A new study has revealed that the epigenetic regulator PRC2 performs different, stage-specific jobs during the earliest phases of mammalian...

A previously unrecognized layer of genome organization has been identified in the mammalian brain, where exceptionally long genes and the...