A large genomic study of East Asian ancestry populations has identified rare copy number variants linked to schizophrenia and, through...

Deep-learning analysis of single-nucleus multi-omic data from flatworms and vertebrates reveals that conserved motif vocabularies maintain cell type family identities...

Researchers report that a technique called TRANsCre-DIONE can convert scar-forming reactive astrocytes into functional motor neurons, a result with implications...

A systematic review and meta-analysis of 25 studies finds that ocular gene therapy significantly suppresses retinal neovascularization and vascular leakage...

Researchers have identified a conserved sequence motif that enables many natural enzymes to use noncanonical redox cofactors, expanding the known...

A new Gene Therapy review charts how mutation-agnostic optogenetic gene therapy could restore vision in blind patients, while detailing the...

A mouse study shows that loss of imprinting of the maternally expressed gene Phlda2 depletes hormone-producing placental cells and restricts...

Researchers have published a detailed protocol for generating totipotent eight-cell embryo-like cells from human pluripotent stem cells without using embryos.

A comprehensive review argues that combining physiological insights with molecular breeding tools such as GWAS, genomic selection and CRISPR editing...

The first genome-wide study of New Zealand's feral Kaimanawa Horses reveals a mixed colonial heritage, dangerously low effective population size...