Proteomic aging clocks have been integrated into a phase 2a clinical trial, enabling simultaneous assessment of geroprotective effects within an...

Researchers found that the immunosuppressant cyclosporine A selectively kills senescent cells by triggering endoplasmic reticulum stress and paraptosis-like death, preventing...

A six-year Swedish cohort study finds that having long-lived parents predicts better cognition, less inflammation, healthier lipids and slower accumulation...

A comprehensive review in Biogerontology argues that engineered nanoparticles could overcome the solubility, stability, and targeting limitations of senolytic drugs,...

A systematic screen of five actin-targeting small molecules in C. elegans finds that only the Arp2/3 inhibitor CK666 reliably shortens...

A pooled analysis of seven randomized trials in older adults shows that caloric restriction improves a composite biomarker index of...

Reframing the global disease burden by age reveals that aging-related conditions now dominate in every income group and uniquely offer...

A Biogerontology Perspective argues that prolonged crises such as the war in Ukraine may biologically accelerate metabolic ageing in older...

A survey of 241 smallholder farmers in Ghana's Oti Region shows that cocoa rehabilitation choices are statistically interdependent and shaped...

A new in vitro study reports that boswellic acid, a frankincense-derived triterpenoid, boosts satellite cell activity, myogenic differentiation, and Akt-mTOR-p70S6K...