In a groundbreaking clinical trial funded by federal grants, researchers from Brown University and Michigan State University have demonstrated a significant advancement in suicide prevention for a high-risk population: individuals recently released from jail. Published in JAMA Network Open, this experimental study presents compelling evidence that targeted safety planning interventions administered during incarceration and maintained through post-release contact can reduce suicide attempts by an impressive 55%. This finding marks a crucial step forward in addressing a public health crisis often overshadowed by broader societal issues.
Suicide risk among formerly incarcerated individuals is alarmingly high, with data suggesting that one in five adults who attempt suicide has spent at least one night in jail within the preceding year. The U.S. experiences over 10 million jail admissions annually, with many detentions lasting only a few days. Despite the transient nature of many incarcerations, jails serve as critical touchpoints for delivering mental health interventions to a population largely disconnected from consistent support mechanisms. The research team hypothesized that proactive intervention during the jail stay, combined with sustained engagement after release, would significantly mitigate the elevated suicide risk seen in this group.
The clinical trial, titled “Suicide Prevention for at-Risk Individuals in Transition,” involved a randomized design enrolling 800 participants from two mid-sized jail systems: the Rhode Island Department of Corrections and Genesee County Jail in Michigan. Following detention, 655 individuals were successfully monitored in the community. The intervention centered on a single, face-to-face safety planning session conducted within the jail, delivered by trained therapists specializing in psychiatric and behavioral health. This session was complemented by a structured telephone follow-up protocol lasting six months after release, emphasizing continuity of care in a community setting—traditionally a challenging environment for formerly incarcerated individuals.
Safety planning is an evidence-based approach previously validated in emergency department settings for patients at risk of suicide. It involves collaborative identification of warning signs, internal coping strategies, access to social supports, and contact information for emergency assistance. The adaptation of this intervention to the jail context required not only clinical skill but also an understanding of the unique stressors and barriers faced by incarcerated individuals. The therapists worked to foster rapport during incarceration and used follow-up calls to assess ongoing risk, troubleshoot daily life challenges, and link participants to community mental health resources, substance abuse treatment, and social services.
Analyses of study outcomes revealed a remarkable 55% reduction in suicide attempts among those receiving the safety planning intervention compared to an enhanced standard of care control group. Furthermore, broader suicide-related events, encompassing suicidal behaviors and hospitalizations, decreased by 42%. These statistically and clinically significant findings underscore the effectiveness of integrating mental health interventions into the detention-release continuum, addressing a critical gap in suicide prevention strategies that often neglect the transitional phase.
The success of this trial illustrates the vital role that correctional and community mental health systems can play in cooperation to support vulnerable individuals. While previous efforts have heavily focused on suicide prevention during incarceration, this study shifts the paradigm by emphasizing both pre-release preparation and intensive follow-up in the community, a period known to carry heightened risk. The early trust established during the jail safety session appears to enhance acceptance and engagement with ongoing care, a factor deemed essential by the investigators.
The research highlighted the complexity of challenges faced by this population, including high rates of preexisting suicide attempts, substance use disorders, trauma histories, and socioeconomic adversity. These intersecting factors contribute to the elevated suicide risk and complicate access to continuous support services. The tailored intervention model accounts for these multidimensional issues by enabling therapists to provide individualized risk assessments, facilitate therapeutic connections, and empower individuals to navigate life stressors post-release.
Lead investigator Lauren Weinstock, a professor of psychiatry and human behavior, emphasized that the crux of this intervention lies in its timing and simplicity. Implementing a brief, focused safety planning session during detention and following it up with regular, supportive telephonic contact may appear modest in scope but yields disproportionate benefits in reducing lethal outcomes. Given the scalability potential and modest resource requirements, this approach holds promise for widespread adoption within correctional systems nationwide.
The researchers are now preparing a detailed cost-effectiveness analysis to inform policymakers and stakeholders about the financial implications and potential savings associated with reduced suicide attempts and hospitalizations. An implementation science phase is planned to assess best practices for integrating this model into routine correctional and community mental health workflows. The ultimate goal is to facilitate system-level changes that institutionalize suicide prevention as a standard part of care for people cycling through the criminal justice system.
This study also builds upon collaborative work with notable experts, including the late psychologist Barbara Stanley from Columbia University and Greg Brown from the University of Pennsylvania, pioneers of the original safety planning intervention in emergency settings. Their foundational work provided the theoretical underpinning and methodological framework, adapted here for a precariously underserved population.
The implications of this research extend beyond the immediate study population, highlighting how brief, targeted psychosocial interventions can be strategically positioned to address complex public health challenges. The integration of clinical psychology, behavioral intervention, and criminal justice reform evidenced in this trial offers a blueprint for future innovations designed to reduce suicide risk and improve mental health outcomes among marginalized groups.
The study’s funding from the National Institute of Mental Health and related institutes underscores the prioritization of suicide prevention as a crucial area for scientific inquiry and public health action. Its findings offer hope for reducing the devastating toll of suicide among individuals who experience incarceration, a group historically overlooked in suicide prevention efforts.
By addressing a critical period of vulnerability and bridging gaps between incarceration and community living, this research showcases the power of proactive mental health intervention. If adopted broadly, such safety planning interventions have the potential to save countless lives, foster recovery, and shift societal perspectives on mental health care in justice-involved populations.
Subject of Research: People
Article Title: Safety planning vs. standard care for suicide prevention after pretrial jail detention: A randomized clinical trial
News Publication Date: 10-Nov-2025
Web References: http://dx.doi.org/10.1001/jamanetworkopen.2025.43156
References: JAMA Network Open, DOI: 10.1001/jamanetworkopen.2025.43156
Keywords: suicide prevention, jail detention, safety planning intervention, randomized clinical trial, mental health, post-release care, criminal justice system, behavioral health, telephone follow-up, suicide risk reduction
