Friday, August 19, 2022
SCIENMAG: Latest Science and Health News
No Result
View All Result
  • Login
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US
No Result
View All Result
Scienmag - Latest science news from science magazine
No Result
View All Result
Home SCIENCE NEWS Medicine & Health

Vanderbilt University Medical Center receives NIH grant to develop artificial kidney

November 3, 2015
in Medicine & Health
0
Share on FacebookShare on Twitter

IMAGE

The National Institutes of Health has awarded a four-year, $6 million grant to investigators at Vanderbilt University Medical Center (VUMC) and the University of California at San Francisco (UCSF) to develop an implantable artificial kidney.

Transplant is the best treatment for kidney failure but donor kidneys are in short supply. According to the U.S. Organ Procurement and Transplantation Network, although more than 109,000 patients in the United States are on the waiting list for a kidney transplant, last year only 17,108 received one, and each day in this country 12 people die awaiting kidney transplant. In all, more than 600,000 Americans have end-stage renal disease, and the annual cost to Medicare from this disease is $32 billion.

The grant will be split evenly between VUMC and UCSF. The principal investigators are VUMC nephrologist William Fissell IV, M.D., associate professor of Medicine and Biomedical Engineering, and UCSF bioengineer Shuvo Roy, Ph.D.

"This project is about creating a permanent solution to the scarcity problem in organ transplantation. We are increasing the options for people with chronic kidney disease who would otherwise be forced onto dialysis," Fissell said. "Dr. Roy and I are pursuing this approach because the integration of silicon nanotechnology and cell culture will achieve a bio-hybrid device within the lifetime of someone who starts dialysis today."

Using semiconductor fabrication techniques originally developed for the microelectronics industry, the bio-artificial kidney weds filters made of silicon with living human kidney cells cultured in the lab from samples harvested from deceased donors. The donated cells form a membrane positioned downstream from the device's intake filter, out of reach of the body's immune response. Organ rejection is not an issue, and the device will run on the body's normal blood pressure — no other power source required.

###

The two investigators are longtime collaborators. In 2003 the kidney project attracted its first NIH funding, and in 2012 the Food and Drug Administration selected the project for a fast-track approval program.

The work is supported by NIH grant 1U01EB021214-01.

Share25Tweet16Share4ShareSendShare
  • Gulf Coast flooding during Hurricane Isaac

    Burying short sections of power lines would drastically reduce hurricanes’ future impact on coastal residents

    77 shares
    Share 31 Tweet 19
  • Reinvigorating ‘lost cause’ exhausted T cells could improve cancer immunotherapy

    171 shares
    Share 68 Tweet 43
  • Climate change threatens food supply chains with cascading impacts on diet quality, income – new modelling shows

    66 shares
    Share 26 Tweet 17
  • Sharpest image ever of universe’s most massive known star

    65 shares
    Share 26 Tweet 16
  • New insights on how some individuals with obesity can lose weight – and keep it off

    68 shares
    Share 27 Tweet 17
  • Obscure gastrointestinal bleeding: rebleeding rates and rebleeding predictors found

    64 shares
    Share 26 Tweet 16
ADVERTISEMENT

About us

We bring you the latest science news from best research centers and universities around the world. Check our website.

Latest NEWS

Reinvigorating ‘lost cause’ exhausted T cells could improve cancer immunotherapy

Allison Institute announces formation of scientific advisory board

How quinine caused World War I (hyperbolic title alert) (video)

Subscribe to Blog via Email

Enter your email address to subscribe to this blog and receive notifications of new posts by email.

Join 194 other subscribers

© 2022 Scienmag- Science Magazine: Latest Science News.

No Result
View All Result
  • HOME PAGE
  • BIOLOGY
  • CHEMISTRY AND PHYSICS
  • MEDICINE
    • Cancer
    • Infectious Emerging Diseases
  • SPACE
  • TECHNOLOGY
  • CONTACT US

© 2022 Scienmag- Science Magazine: Latest Science News.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In