Temple researchers reverse cognitive impairments in mice with dementia
(Temple University Health System) Reversing memory deficits and impairments in spatial learning is a major goal in dementia research. A lack of knowledge about cellular pathways critical to the development of dementia has prevented significant clinical advance. Researchers at Temple's Lewis Katz School of Medicine are breaking through that barrier. They show, for the first time in an animal model, that a drug can reverse tau pathology — the second-most important lesion in the brain in patients with Alzheimer's.