Transition-age youth face an elevated risk of psychiatric disorders and significant discontinuities when moving from child and adolescent mental health services into adult services. The review examined early-intervention models proposed to address this “transition gap,” including clinical staging and transdiagnostic approaches. Researchers followed PRISMA 2020 guidelines and searched five databases—PubMed, PsycINFO, Scopus, ProQuest and Cochrane—for publications released between 2013 and 2025.

Eligible work included quantitative, qualitative and mixed-methods studies describing service models or early interventions for transition-age youth. Methodological quality was assessed with design-specific tools: AMSTAR, the Newcastle-Ottawa Scale, Jadad and SANRA. Overall ratings were moderate to good, but observational and longitudinal designs predominated.

Across countries and settings, the included studies repeatedly emphasized accessible, youth-friendly environments, support for autonomy and functional recovery, multidisciplinary integration, preventive care, societal engagement, continuity between services and economic evaluation. Integrated hubs and structured transition protocols were consistently associated with less disengagement from care. Preventive strategies targeting subthreshold symptoms also appeared feasible and showed early signs of efficacy.

These results should be interpreted as associations and early signals rather than proof that any particular model causes improved long-term psychiatric outcomes. Implementation remained uneven despite these encouraging findings. The review identified variation in how faithfully services delivered their proposed models, along with systemic barriers such as the lack of national transition protocols, insufficient resources and uneven access.

The authors conclude that youth-friendly, integrated and preventive approaches are central to effective service design, but sustainability and equitable access will require system-wide and policy-level reform. Future research should prioritize direct comparisons among models, longer-term outcomes and evaluations of how early interventions can be incorporated into routine practice across diverse health systems.

Subject of Research: Systematic review of early-intervention mental health service models for transition-age youth

Article Title: Early interventions in transition-age youth: a systematic review

Article References: Keiser, J., Zaina, G., Ben-Shaool, E., Fongaro, E., Reis, J., Purper-Ouakil, D., Delvenne, V., Marchini, S., & Nicolis, H. (2026). Early interventions in transition-age youth: a systematic review. BMC Psychiatry. https://doi.org/10.1186/s12888-026-08778-4

Image Credits: AI Generated

DOI: 10.1186/s12888-026-08778-4

Keywords: transition-age youth, mental health services, early intervention, continuity of care, service integration, transition protocols, functional recovery, preventive care, systematic review, Early, interventions, transition-age