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	<title>Pkhd1 and Tfap2b gene regulation &#8211; Science</title>
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	<title>Pkhd1 and Tfap2b gene regulation &#8211; Science</title>
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		<title>Deletion of ARPKD-associated Pkhd1 gene in mice results in decreased Tfap2b expression and eye abnormalities</title>
		<link>https://scienmag.com/deletion-of-arpkd-associated-pkhd1-gene-in-mice-results-in-decreased-tfap2b-expression-and-eye-abnormalities/</link>
		
		<dc:creator><![CDATA[Juliet Wilcox]]></dc:creator>
		<pubDate>Wed, 29 Jul 2026 20:57:13 +0000</pubDate>
				<category><![CDATA[Medicine]]></category>
		<category><![CDATA[ARPKD mouse model]]></category>
		<category><![CDATA[ARPKD-associated gene function]]></category>
		<category><![CDATA[congenital eye abnormalities]]></category>
		<category><![CDATA[developmental eye defects in mice]]></category>
		<category><![CDATA[eye abnormalities in genetic mouse models]]></category>
		<category><![CDATA[gene knockout studies in mice]]></category>
		<category><![CDATA[Pkhd1 and Tfap2b gene regulation]]></category>
		<category><![CDATA[Pkhd1 gene deletion effects]]></category>
		<category><![CDATA[polycystic kidney disease genetics]]></category>
		<category><![CDATA[polycystic kidney disease research]]></category>
		<category><![CDATA[renal and ocular phenotypes in ARPKD]]></category>
		<category><![CDATA[Tfap2b gene expression changes]]></category>
		<guid isPermaLink="false">https://scienmag.com/deletion-of-arpkd-associated-pkhd1-gene-in-mice-results-in-decreased-tfap2b-expression-and-eye-abnormalities/</guid>

					<description><![CDATA[Ishimoto, Y., Menezes, L.F., Nakaya, N. et al. Deletion of ARPKD-associated Pkhd1 gene in mice results in decreased Tfap2b expression and eye abnormalities. Nat Commun (2026).]]></description>
										<content:encoded><![CDATA[<p class="c-bibliographic-information__citation">Ishimoto, Y., Menezes, L.F., Nakaya, N. <i>et al.</i> Deletion of ARPKD-associated <i>Pkhd1</i> gene in mice results in decreased <i>Tfap2b</i> expression and eye abnormalities.<br />
                    <i>Nat Commun</i>  (2026). </p>
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