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	<title>forensic radiology &#8211; Science</title>
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	<title>forensic radiology &#8211; Science</title>
	<link>https://scienmag.com</link>
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		<title>MRI Study Splits Bone Growth Stage Into Three Substages to Sharpen Forensic Age Tests</title>
		<link>https://scienmag.com/mri-study-splits-bone-growth-stage-into-three-substages-to-sharpen-forensic-age-tests/</link>
		
		<dc:creator><![CDATA[Ophelia Keating]]></dc:creator>
		<pubDate>Fri, 25 Sep 2026 22:00:51 +0000</pubDate>
				<category><![CDATA[Medicine]]></category>
		<category><![CDATA[adolescent skeletal maturity assessment]]></category>
		<category><![CDATA[challenges in legal age verification]]></category>
		<category><![CDATA[epiphyseal closure in long bones]]></category>
		<category><![CDATA[fine-grained staging of bone growth]]></category>
		<category><![CDATA[forensic age estimation]]></category>
		<category><![CDATA[forensic radiology]]></category>
		<category><![CDATA[forensic radiology techniques]]></category>
		<category><![CDATA[growth plate]]></category>
		<category><![CDATA[knee joint]]></category>
		<category><![CDATA[knee joint development in forensic science]]></category>
		<category><![CDATA[legal age determination methods]]></category>
		<category><![CDATA[legal age thresholds]]></category>
		<category><![CDATA[limitations of MRI in age testing]]></category>
		<category><![CDATA[MRI]]></category>
		<category><![CDATA[MRI classification of growth stages]]></category>
		<category><![CDATA[MRI-based bone growth staging]]></category>
		<category><![CDATA[ossification]]></category>
		<category><![CDATA[pilot study]]></category>
		<category><![CDATA[proximal tibial epiphysis]]></category>
		<category><![CDATA[proximal tibial epiphysis development]]></category>
		<category><![CDATA[radiation-free imaging]]></category>
		<category><![CDATA[skeletal maturation]]></category>
		<category><![CDATA[Vieth staging]]></category>
		<guid isPermaLink="false">https://scienmag.com/?p=214810</guid>

					<description><![CDATA[German researchers split a key MRI bone maturity stage into three finer substages and found the refinement is feasible but cannot reliably confirm whether a person has reached age sixteen or eighteen.]]></description>
										<content:encoded><![CDATA[<p>When courts must decide whether a young person without valid documents is a minor or an adult, forensic experts turn to the skeleton for answers. The growth plates, or epiphyses, of long bones close in a predictable sequence during adolescence, and the state of that closure offers a window into chronological age. Now a team of German researchers has taken a closer look at one specific stage of knee development, asking whether a coarse category long used in magnetic resonance imaging could be split into finer steps to yield more precise legal answers. Their pilot study, published in the International Journal of Legal Medicine, shows that the finer classification is technically feasible, but it also reveals sobering limits on what this particular bone region can tell investigators about the most important legal age thresholds.</p>
<p>The work centers on the proximal tibial epiphysis, the growth plate at the upper end of the shinbone just below the knee joint. In 2018, Vieth and colleagues introduced an MRI-based staging system for this region that has since been validated by several independent research groups. The system&#8217;s most celebrated feature is its stage 6, which in male individuals was observed only after the eighteenth birthday, making it a potential marker of legal adulthood. Because magnetic resonance imaging involves no ionizing radiation, unlike computed tomography of the clavicles that is currently recommended when hand skeletal development is complete, MRI of the knee has been promoted as a more ethically acceptable tool for age estimation in living subjects.</p>
<p>Yet the earlier validation work by the same German group hinted at something else: stage 4, a mid-range category in which the growth plate is partially fused, might contain hidden structure. If the stage could be subdivided, perhaps the substages would align more closely with legally relevant ages such as fourteen, sixteen, or eighteen years. The new pilot study, led by Natia Chitavishvili of Jena University Hospital together with Daniel Wittschieber, Maria L. Hahnemann, and colleagues, set out to test that idea using a cohort of fifty-seven T1-weighted MRI examinations, twenty-four from males and thirty-three from females, all previously assigned to Vieth stage 4.</p>
<p>The technical logic behind the subclassification rests on a thin line of intermediate signal intensity that appears within the growth plate on T1-weighted turbo spin-echo images. This line represents the advancing front of bony fusion across the metaphysis. The researchers divided its extent relative to the total metaphyseal width into three categories: substage 4a when the line spans less than one-third of the width, substage 4b when it spans between one-third and two-thirds, and substage 4c when it exceeds two-thirds. Three experienced readers, a clinical radiologist, a pediatric radiologist, and a forensic medicine specialist, assessed only coronal images and evaluated every slice of the epiphysis, blinded to each subject&#8217;s age and sex throughout.</p>
<p>The results confirmed that every one of the fifty-seven cases could be placed into one of the three substages, demonstrating that the morphological criteria are workable in practice. Reliability statistics supported the scheme as well. Intra-observer agreement, measured when the first reader repeated all assessments two months after the initial consensus reading, yielded a Cohen&#8217;s kappa of 0.751, and inter-observer agreement between the first two readers reached 0.663. Under the conventional interpretation scale, both values fall within the range of good agreement, suggesting that different trained readers can apply the substages consistently.</p>
<p>The age data, however, tell a more complicated story. Among male subjects, the minimum ages at which substages 4a, 4b, and 4c were first observed were 15.45, 15.68, and 15.23 years respectively, meaning all three substages appeared only after the fourteenth birthday. Among females, the corresponding minimum ages were 12.64, 12.57, and 13.18 years. Statistically significant sex differences emerged for substages 4b and 4c, consistent with the well-documented pattern in which girls reach skeletal milestones roughly two years earlier than boys. In both sexes, substage 4c showed a particularly wide spread of chronological ages, weakening its value as a narrow age indicator.</p>
<p>What does this mean for the courtroom? The authors conclude that the substages may assist in verifying completion of the fourteenth year of life, at least in males, since no male in the cohort displayed any substage before age 15. But the crucial thresholds of sixteen and eighteen years, which drive decisions about criminal responsibility, asylum, and majority in many jurisdictions, could not be reliably verified with this subclassification. The broad age distributions, especially within substage 4c, mean that an individual at that substage could plausibly be anywhere within a multi-year window that straddles the legal boundaries that matter most.</p>
<p>The findings fit into a broader research landscape. Krämer and colleagues demonstrated as early as 2014 that substage assessment of the proximal tibial epiphysis by MRI was feasible, using an adapted system derived from the clavicle staging schemes of Schmeling and Kellinghaus, and reported minimum ages in comparable ranges. Ottow and colleagues expanded on that work in 2017 with 658 knee MRI scans from individuals aged twelve to twenty-four. More recently, Ekizoglu and colleagues introduced novel substages based on the Dedouit classification using MERGE sequences in 559 individuals, reporting minimum ages that likewise fell within similar age bands. Notably, the Dedouit approach has been criticized because it relies on absolute measurements of growth plate layer thickness, which may vary with body size and thereby introduce bias, whereas the Vieth system and its new substages rest on proportional, morphological criteria.</p>
<p>The authors are candid about the limitations of their pilot. With only fifty-seven cases, the numbers assigned to each substage were small, and substage 4a appeared in just five individuals, which limits the statistical power of the analysis. The retrospective design meant that scans came from different scanners at 1.5 and 3.0 Tesla with non-uniform clinical protocols, a heterogeneity that mirrors real-world practice but complicates precise morphological differentiation. The cohort, drawn from hospital records in Thuringia, was also predominantly Western Caucasian with a largely high socioeconomic background, raising questions about generalizability to the diverse populations that forensic age estimation actually serves. The researchers emphasize that the subclassification cannot currently be recommended for routine forensic practice without validation in larger, independent study populations.</p>
<p>Even so, the study adds a meaningful piece to the puzzle of skeletal maturation. It demonstrates that the intermediate signal line within the fusing tibial growth plate progresses in a graded, readable fashion, and it maps that progression onto chronological age with sex-specific reference values. Future prospective studies with standardized MRI protocols and larger multicenter cohorts may clarify whether the substages gain diagnostic value, particularly around the fourteenth-year threshold in males. For now, the message for forensic science is one of tempered expectation: the knee can speak about age, but its vocabulary at stage 4 remains too coarse to settle the sixteen- and eighteen-year questions that matter most in law.</p>
<p><strong>Subject of Research:</strong> MRI-based subclassification of proximal tibial epiphysis ossification for forensic age estimation</p>
<p><strong>Article Title:</strong> Subclassification of Vieth stage 4 in MRI of the proximal tibial epiphysis: a pilot study for forensic age estimation</p>
<p><strong>Article References:</strong> Chitavishvili, N., Wittschieber, D., Papageorgiou, I., Malich, A., Mentzel, H.-J., &amp; Hahnemann, M. L. (2026). Subclassification of Vieth stage 4 in MRI of the proximal tibial epiphysis: a pilot study for forensic age estimation. <em>International Journal of Legal Medicine</em>. <a href="https://doi.org/10.1007/s00414-026-03991-y" rel="noopener noreferrer">https://doi.org/10.1007/s00414-026-03991-y</a></p>
<p><strong>Image Credits:</strong> AI Generated</p>
<p><strong>DOI:</strong> <a href="https://doi.org/10.1007/s00414-026-03991-y" rel="noopener noreferrer">10.1007/s00414-026-03991-y</a></p>
<p><strong>Keywords:</strong> forensic age estimation, MRI, proximal tibial epiphysis, Vieth staging, growth plate, ossification, knee joint, forensic radiology, radiation-free imaging, skeletal maturation, legal age thresholds, pilot study</p>
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		<post-id xmlns="com-wordpress:feed-additions:1">214810</post-id>	</item>
		<item>
		<title>A Decade of Postmortem Imaging Is Quietly Transforming Paediatric Autopsy Practice</title>
		<link>https://scienmag.com/a-decade-of-postmortem-imaging-is-quietly-transforming-paediatric-autopsy-practice/</link>
		
		<dc:creator><![CDATA[Harold Sullivan]]></dc:creator>
		<pubDate>Fri, 25 Sep 2026 09:55:19 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[advancements in pediatric postmortem imaging technology]]></category>
		<category><![CDATA[autopsy consent rates and cultural barriers]]></category>
		<category><![CDATA[ESPR task force]]></category>
		<category><![CDATA[family and cultural considerations in pediatric autopsy]]></category>
		<category><![CDATA[fetal and neonatal postmortem imaging]]></category>
		<category><![CDATA[fetal imaging]]></category>
		<category><![CDATA[forensic radiology]]></category>
		<category><![CDATA[impact of postmortem imaging on clinical care]]></category>
		<category><![CDATA[integration of postmortem imaging in pediatric forensic investigations]]></category>
		<category><![CDATA[international pediatric radiology collaborations]]></category>
		<category><![CDATA[less-invasive autopsy]]></category>
		<category><![CDATA[minimally invasive autopsy techniques]]></category>
		<category><![CDATA[paediatric postmortem imaging]]></category>
		<category><![CDATA[paediatric radiology]]></category>
		<category><![CDATA[pediatric autopsy transformation]]></category>
		<category><![CDATA[pediatric radiology]]></category>
		<category><![CDATA[perinatal autopsy]]></category>
		<category><![CDATA[photon-counting CT]]></category>
		<category><![CDATA[postmortem CT]]></category>
		<category><![CDATA[postmortem imaging]]></category>
		<category><![CDATA[postmortem MRI]]></category>
		<category><![CDATA[role of imaging in unexplanned child deaths]]></category>
		<category><![CDATA[standardization of pediatric autopsy protocols]]></category>
		<category><![CDATA[structured reporting]]></category>
		<guid isPermaLink="false">https://scienmag.com/?p=214299</guid>

					<description><![CDATA[A new commentary in Pediatric Radiology charts how a decade of international collaboration, standardized protocols and multi-society guidelines has transformed fetal and paediatric postmortem imaging from scattered practice into an emerging clinical service.]]></description>
										<content:encoded><![CDATA[<p>When two paediatric radiologists published a short commentary in 2015 under the Latin motto &#8220;mortui vivos docent&#8221; — the dead teach the living — postmortem imaging in children was a fragmented, largely ad hoc enterprise. Ten years later, Owen J. Arthurs of Great Ormond Street Hospital for Children and Rick R. van Rijn of Amsterdam University Medical Centers and the Netherlands Forensic Institute have returned to the pages of Pediatric Radiology to take stock of that decade, and the picture they describe is one of remarkable, if uneven, transformation. Their new commentary, published in September 2026, traces how fetal and paediatric postmortem imaging has moved from scattered local practice to a field with international task forces, standardized protocols, multi-society endorsement and, increasingly, a defined place in clinical care.</p>
<p>The central premise of the field has not changed: imaging the dead can answer questions that matter enormously for the living. When a fetus dies in utero, when a newborn succumbs shortly after birth, or when a child dies unexpectedly, families and clinicians want answers. Conventional autopsy has long been the gold standard, but consent rates for full autopsy have fallen across much of the world, driven by religious and cultural concerns, emotional distress and simple unfamiliarity with the procedure. Less-invasive alternatives that use imaging — chiefly postmortem computed tomography and postmortem magnetic resonance imaging — promise a way to recover diagnostic information while respecting families&#8217; wishes. That promise, the commentary argues, has come substantially closer to reality over the past ten years.</p>
<p>The turning point came in organizational form. In 2016, the European Society of Paediatric Radiology convened a dedicated postmortem imaging task force, building on an earlier questionnaire-based survey that had revealed how inconsistent practice was across European centres. That survey, published in 2014, documented wide variation in whether imaging was offered at all, which modalities were used, and how results were reported. The task force gave the field a focal point: a standing group of experts who could translate scattered research findings into practical, consensus-based guidance. The commentary&#8217;s authors, who have led much of this effort, frame the past decade as the story of what happened once that structure existed.</p>
<p>The most tangible products of that structure are the protocols. In 2019, a joint working group of the European Society of Paediatric Radiology and the International Society for Forensic Radiology and Imaging published the first standardized protocol for paediatric postmortem computed tomography, specifying how scans should be acquired in children of different sizes and ages. More recently, the task force has turned to magnetic resonance imaging, publishing a referral template for fetal and neonatal postmortem imaging in 2024, a full clinical protocol for fetal and neonatal postmortem MRI in 2025, and, in 2026, recommendations for standardized structured reporting of those examinations. Reporting guidance for perinatal and paediatric postmortem CT followed a parallel track, published in Insights into Imaging in 2024.</p>
<p>Standardized reporting deserves particular emphasis because it addresses one of the field&#8217;s most stubborn problems. An imaging study is only as useful as the report that follows it, and early adopters of postmortem MRI found that radiologists described findings in wildly different ways, making it difficult to compare results across centres or to accumulate the evidence base needed to convince coroners, pathologists and funders. The 2026 structured reporting recommendations aim to fix this by defining what must be documented, in what order and with what terminology, so that a postmortem MRI report from Amsterdam can be read and trusted in London, Toronto or Melbourne. It is the kind of unglamorous infrastructure work that rarely makes headlines but determines whether a technique becomes routine or remains a curiosity.</p>
<p>The evidence base itself has grown in parallel. One of the decade&#8217;s most influential studies, the DRIFT trial published in The Lancet Child &amp; Adolescent Health in 2018, compared chest radiographs with computed tomography for detecting rib fractures in children and provided diagnostic accuracy data that directly inform how skeletal injury should be assessed after death. Other work has pushed into more sophisticated territory: diffusion-weighted postmortem MRI of the fetal brain has been used to help time perinatal deaths, a question with real forensic and medico-legal significance, while feasibility studies have explored multiparametric mapping and spectroscopy approaches that quantify the biochemical changes tissues undergo after death. These quantitative techniques remain largely research tools, but they hint at a future in which postmortem imaging does more than mirror autopsy — it measures things autopsy cannot.</p>
<p>Geography, however, remains a limiting factor. A 2023 survey of North American practice found that paediatric postmortem imaging is used far less consistently there than the European literature might suggest, and a companion European survey published the same year examined the fragile funding streams that support the work. Postmortem imaging often falls between budgetary stools: it is not routine diagnostic imaging with a living patient, nor is it always funded as part of forensic or medico-legal investigation. The commentary is candid that reimbursement and sustainable financing are now among the biggest obstacles to wider adoption, perhaps bigger than any technical question about image quality or diagnostic accuracy.</p>
<p>The institutional response has been to widen the coalition. In 2026, a multi-society statement on implementing paediatric and fetal postmortem imaging into clinical practice was issued jointly by the European Society of Paediatric Radiology, the Society for Pediatric Radiology, the Latin American Society of Pediatric Radiology, the Asian and Oceanic Society for Pediatric Radiology, the World Federation of Pediatric Imaging and the International Association of Forensic Radiographers. That breadth matters. It signals that the field is no longer a European project but a global one, and it gives radiologists, pathologists, coroners and health administrators on multiple continents a common reference point when they argue for local services.</p>
<p>Technology continues to move as well. Among the developments highlighted in the commentary&#8217;s own journal is early experience with photon-counting detector CT in paediatric postmortem imaging, a detector technology that offers higher spatial resolution and improved tissue contrast at comparable or lower radiation exposure than conventional CT. For a field whose credibility depends on detecting small, subtle findings — a hairline rib fracture, a tiny intracranial haemorrhage, a subtle malformation — such hardware advances could meaningfully shift diagnostic performance. The commentary also notes the publication of a comprehensive textbook on postmortem imaging of the fetus and child in 2025, consolidating a decade of accumulated knowledge into a single reference for practitioners entering the field.</p>
<p>Where does the field go from here? The commentary&#8217;s implicit answer is that the scientific groundwork has largely been laid and the remaining battles are organizational: funding, service implementation, training and the slow work of convincing legal systems and bereaved families that imaging can stand alongside — or in some cases replace — conventional autopsy. For early pregnancy loss, less-invasive autopsy approaches have already been shown to offer families answers where a full autopsy would be declined. The decade since &#8220;mortui vivos docent&#8221; has not eliminated the need for pathologists, and few in the field claim it should; instead, imaging has become a complementary tool that can guide autopsy, replace it when families refuse it, and extract information from bodies that must otherwise go unexamined. The dead, it turns out, teach the living best when the living build the systems to listen.</p>
<p><strong>Subject of Research:</strong> Paediatric and perinatal postmortem imaging</p>
<p><strong>Article Title:</strong> 10 years of paediatric and perinatal postmortem imaging: where are we now?</p>
<p><strong>Article References:</strong> Arthurs, O. J., &amp; van Rijn, R. R. (2026). 10 years of paediatric and perinatal postmortem imaging: where are we now?. <em>Pediatric Radiology</em>. <a href="https://doi.org/10.1007/s00247-026-06795-9" rel="noopener noreferrer">https://doi.org/10.1007/s00247-026-06795-9</a></p>
<p><strong>Image Credits:</strong> AI Generated</p>
<p><strong>DOI:</strong> <a href="https://doi.org/10.1007/s00247-026-06795-9" rel="noopener noreferrer">10.1007/s00247-026-06795-9</a></p>
<p><strong>Keywords:</strong> postmortem imaging, paediatric radiology, perinatal autopsy, postmortem MRI, postmortem CT, ESPR task force, less-invasive autopsy, fetal imaging, forensic radiology, structured reporting, photon-counting CT, Pediatric Radiology</p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">214299</post-id>	</item>
		<item>
		<title>Your Jawbone Could Reveal Your Sex With Over 90 Percent Accuracy, New Study Shows</title>
		<link>https://scienmag.com/your-jawbone-could-reveal-your-sex-with-over-90-percent-accuracy-new-study-shows/</link>
		
		<dc:creator><![CDATA[Peter Mason]]></dc:creator>
		<pubDate>Sun, 13 Sep 2026 03:11:36 +0000</pubDate>
				<category><![CDATA[Medicine]]></category>
		<category><![CDATA[3D CT scan reconstruction]]></category>
		<category><![CDATA[3D imaging]]></category>
		<category><![CDATA[accuracy of bone-based sex prediction]]></category>
		<category><![CDATA[bigonial distance]]></category>
		<category><![CDATA[computed tomography]]></category>
		<category><![CDATA[discriminant analysis]]></category>
		<category><![CDATA[forensic anthropology]]></category>
		<category><![CDATA[forensic imaging techniques]]></category>
		<category><![CDATA[forensic radiology]]></category>
		<category><![CDATA[forensic science research]]></category>
		<category><![CDATA[human identification]]></category>
		<category><![CDATA[human remains identification]]></category>
		<category><![CDATA[jawbone sex estimation]]></category>
		<category><![CDATA[logistic regression]]></category>
		<category><![CDATA[mandible]]></category>
		<category><![CDATA[mandible morphometric analysis]]></category>
		<category><![CDATA[morphometry]]></category>
		<category><![CDATA[osteometric analysis]]></category>
		<category><![CDATA[population-specific skeletal markers]]></category>
		<category><![CDATA[sex estimation]]></category>
		<category><![CDATA[sexual dimorphism]]></category>
		<category><![CDATA[sexual dimorphism in human bones]]></category>
		<category><![CDATA[skeletal sex determination]]></category>
		<guid isPermaLink="false">https://scienmag.com/?p=201176</guid>

					<description><![CDATA[Turkish researchers used 3D reconstructions of computed tomography scans to show that simple mandibular measurements can estimate sex with cross-validated accuracy approaching 90 percent.]]></description>
										<content:encoded><![CDATA[<p>When forensic investigators recover human remains, one of the first and most fundamental questions they must answer is simple to ask but often difficult to answer: was this person male or female? A new study published in the International Journal of Legal Medicine suggests that the answer may lie, quite literally, in the jaw. Researchers from Süleyman Demirel University, Karamanoğlu Mehmetbey University, Lokman Hekim University and Kocaeli City Hospital in Türkiye have demonstrated that the mandible, the largest and strongest bone of the human face, can be used to estimate sex with accuracy rates exceeding ninety percent, using nothing more than three-dimensional reconstructions of routine computed tomography scans.</p>
<p>The study, led by Yadigar Kastamoni and Kenan Öztürk of the Department of Anatomy at Süleyman Demirel University, together with Ahmet Dursun, Onur Can Şanlı and radiologist Veysel Atilla Ayyıldız, set out to reveal sex-related characteristics through morphometric measurements taken on the mandible, and to predict sex in individuals from different age groups using those variables. The work addresses one of the enduring challenges of forensic anthropology: identifying reliable, population-appropriate skeletal markers of sexual dimorphism that remain robust across the adult lifespan.</p>
<p>The research team analysed head and neck computed tomography images from 152 individuals, 77 males and 75 females, aged between 20 and 98 years. From these scans, the researchers generated three-dimensional reconstructions of each mandible using the RadiAnt DICOM viewer, a software platform that converts the two-dimensional slice data produced by CT scanners into volumetric models that can be measured in three dimensions. This approach reflects a broader shift in forensic science away from measurements taken with calipers on dry skulls and toward virtual anthropology, in which clinical imaging archives become rich sources of skeletal data.</p>
<p>The specific landmarks chosen for measurement were carefully selected regions of the mandible with well-established anatomical identities. The team measured dimensions relating to the foramen mentale, the mental foramen through which the mental nerve and vessels emerge on the front of the jaw; the condylus mandibulae, the rounded condyles that articulate with the skull at the temporomandibular joints; the incisura mandibulae, the notch between the condyle and the coronoid process on the upper margin of the ramus; and the angulus mandibulae, the angle of the jaw at the back and lower corner of the bone. In addition, the researchers measured the bigonial distance, the straight-line breadth of the jaw between the two gonion points at the angles on either side. All measurements, except those involving the mandibular angle, were carried out in RadiAnt DICOM Viewer 2020.1.1, and the resulting data were analysed statistically using SPSS 20.0 for Windows.</p>
<p>The results were strikingly consistent with the known biology of the human mandible. When the parameters were compared between the sexes, the mean values of all measurements, with the single exception of the left mandibular angle, were larger in males than in females. This pattern mirrors the influence of testosterone-driven bone growth during puberty, which produces a generally larger, squarer and more robust jaw in men, while hormonal and muscular factors in women tend to produce a jaw with a more obtuse gonial angle and finer proportions. The only measurement that failed to show a statistically significant sex difference was the gonial angle itself on the left side, a finding that reinforces a long-standing caution in the literature: angular measures of the jaw are notoriously variable and are influenced by age-related remodelling, tooth loss and chewing forces.</p>
<p>The degree of sexual dimorphism varied considerably across the measured parameters. The highest dimorphism rate was observed in the incisura mandibulae, the mandibular notch, which differed between the sexes by 14.39 percent on the right side and 14.29 percent on the left. At the opposite extreme, the angulus mandibulae showed almost no dimorphism, with differences of just 0.12 percent on the right and 0.57 percent on the left. This gradient is informative for forensic practice: it suggests that linear distances spanning the ramus, particularly between the mandibular condyle and the gonion, carry far more sex-diagnostic information than the angle of the jaw, which should be treated with caution when sexing fragmentary remains.</p>
<p>Indeed, the statistically significant differences between the sexes were found specifically in the distances from the condylus mandibulae to the gonion on both sides of the jaw, alongside the bigonial distance. These findings give forensic anthropologists a small set of hardy landmarks, robust bony points that survive decomposition and trauma relatively well, from which reliable linear measurements can be taken. Because the condyle and gonion are prominent structures on the ramus, they remain measurable even when the delicate alveolar portion of the jaw bearing the teeth has been damaged or lost, a common scenario in archaeological and forensic contexts.</p>
<p>What elevates the study beyond a simple descriptive anatomy exercise is its predictive modelling. The researchers built a logistic regression model from their measured variables, which correctly classified 91.4 percent of individuals in the development sample. A parallel discriminant function analysis achieved 90.1 percent classification accuracy on the original sample, and, crucially, retained 85.5 percent accuracy under leave-one-out cross-validation, a stringent test in which each individual is classified by a model trained on everyone else. The modest drop between original and cross-validated performance indicates that the model generalises reasonably well rather than simply memorising the training data, an important consideration for any method intended for real casework.</p>
<p>The authors conclude that sex estimation can be successfully performed using external measurements of the mandible, and they highlight the bigonial distance and the gonion-to-condyle measurements as particularly valuable parameters for sex differentiation. They suggest the method may prove useful in anatomy, forensic medicine and anthropology, especially in studies requiring sex estimation. This positions the mandible alongside the pelvis and skull as a first-rank bone for sex estimation, with particular value in contexts where those more classically dimorphic elements are missing. The mandible is also among the densest and most durable bones in the human skeleton, frequently surviving fire, fragmentation and long burial, which makes any validated method for reading sex from it disproportionately useful.</p>
<p>The study also carries broader implications for how forensic science will develop in the coming years. Computed tomography is now routinely performed in hospitals worldwide, and archives of clinical scans represent vast, untapped populations of reference data. Virtual osteometry of this kind does not require a physical skeleton at all: it can be applied ante-mortem to living patients in identification contexts, and post-mortem using clinical or forensic CT, avoiding destructive sampling of evidence. Earlier work cited by the team, including validation studies of three-dimensional CT measurements and postmortem CT morphometry of the mandible in Japanese populations, had already established the technical reliability of imaging-based measurement; the new study extends that framework with a large, wide-ranging adult sample spanning nearly eight decades of age, from 20 to 98 years.</p>
<p>As with all skeletal sex-estimation methods, population specificity remains the central caveat. The dimensions of the mandible vary across ancestral and geographic groups, and the classification functions derived here were developed on a Turkish sample; forensic practitioners applying them elsewhere would need to validate or recalibrate the model against local reference data before relying on it in identification casework. The retrospective design, approved by the Human Research Ethics Committee of Süleyman Demirel University with informed consent waived for anonymised data, also means the findings describe a clinical imaging population rather than a random demographic one. Nevertheless, with cross-validated accuracy approaching ninety percent from a handful of simple linear measurements, the message of the study is clear and, for a field where even a single additional clue can resolve an identification, quietly revolutionary: the jawbone remembers who you were, and it is willing to tell.</p>
<p><strong>Subject of Research:</strong> Sex estimation from morphometric measurements of the human mandible in three-dimensional computed tomography images</p>
<p><strong>Article Title:</strong> Sex estimation from the mandible in 3D computed tomography images</p>
<p><strong>Article References:</strong> Kastamoni, Y., Dursun, A., Şanlı, O. C., Ayyıldız, V. A., &amp; Öztürk, K. (2026). Sex estimation from the mandible in 3D computed tomography images. <em>International Journal of Legal Medicine</em>. <a href="https://doi.org/10.1007/s00414-026-04001-x" rel="noopener noreferrer">https://doi.org/10.1007/s00414-026-04001-x</a></p>
<p><strong>Image Credits:</strong> AI Generated</p>
<p><strong>DOI:</strong> <a href="https://doi.org/10.1007/s00414-026-04001-x" rel="noopener noreferrer">10.1007/s00414-026-04001-x</a></p>
<p><strong>Keywords:</strong> sexual dimorphism, mandible, computed tomography, forensic anthropology, 3D imaging, morphometry, sex estimation, bigonial distance, logistic regression, discriminant analysis, human identification, osteometric analysis</p>
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		<post-id xmlns="com-wordpress:feed-additions:1">201176</post-id>	</item>
		<item>
		<title>Rare Radiopaque Ring on Postmortem CT Marks Contact Gunshot Wounds, Study Finds</title>
		<link>https://scienmag.com/rare-radiopaque-ring-on-postmortem-ct-marks-contact-gunshot-wounds-study-finds/</link>
		
		<dc:creator><![CDATA[Ophelia Keating]]></dc:creator>
		<pubDate>Sat, 12 Sep 2026 17:20:30 +0000</pubDate>
				<category><![CDATA[Medicine]]></category>
		<category><![CDATA[contact gunshot wound indicators]]></category>
		<category><![CDATA[contact shot]]></category>
		<category><![CDATA[entry wound]]></category>
		<category><![CDATA[firearm injury trauma patterns]]></category>
		<category><![CDATA[firearm wound differentiation]]></category>
		<category><![CDATA[forensic imaging]]></category>
		<category><![CDATA[forensic imaging techniques]]></category>
		<category><![CDATA[forensic investigation of gunshot injuries]]></category>
		<category><![CDATA[forensic radiology]]></category>
		<category><![CDATA[gunshot residue]]></category>
		<category><![CDATA[gunshot residue visualization]]></category>
		<category><![CDATA[gunshot wound analysis]]></category>
		<category><![CDATA[hyperdense rim sign]]></category>
		<category><![CDATA[PMCT in forensic pathology]]></category>
		<category><![CDATA[postmortem CT]]></category>
		<category><![CDATA[postmortem CT imaging]]></category>
		<category><![CDATA[Radiopaque]]></category>
		<category><![CDATA[radiopaque ring sign]]></category>
		<category><![CDATA[ring]]></category>
		<category><![CDATA[virtual autopsy]]></category>
		<category><![CDATA[wound ballistics]]></category>
		<category><![CDATA[wound contact assessment]]></category>
		<guid isPermaLink="false">https://scienmag.com/?p=196919</guid>

					<description><![CDATA[A rare compact ring of radiopaque material on postmortem CT appears confined to entry wounds from contact shots, offering forensic investigators a new morphological marker.]]></description>
										<content:encoded><![CDATA[<p>Forensic radiologists in Zurich have identified a strikingly rare imaging feature that could sharpen one of the most consequential judgments in gunshot death investigations: distinguishing an entry wound from an exit wound, and in some cases inferring how close the muzzle was to the skin when the trigger was pulled. In a retrospective analysis of fifty forensic cases published in the International Journal of Legal Medicine, researchers at the Institute of Forensic Medicine, University of Zurich report that a compact, well-demarcated ring of radiopaque material at the wound margin—dubbed the radiopaque ring sign—appeared in only three of fifty cases, or six percent of the cohort. All three of those cases, the team found, involved revolvers and external findings consistent with contact shots, suggesting the sign may be tied to very specific firing conditions rather than being a universal feature of gunshot residue deposition.</p>
<p>Postmortem computed tomography, or PMCT, has become a mainstay of modern forensic investigation, offering a non-invasive window into projectile trajectories, fracture patterns, and the extensive osseous destruction typical of cranial gunshot injuries. Established PMCT findings include inward and outward bevelling of bone, keyhole lesions, radiating fracture lines, and the distribution of bone fragments, air, and blood along the bullet path. Yet comparatively little systematic attention has been paid to the hyperdense—radiographically bright—findings that appear at the entry wound itself. These bright foci are frequently attributed to gunshot residue, the particulate and combustion-related material expelled from a firearm upon discharge, but their morphology and underlying mechanisms have remained poorly differentiated, despite their potential forensic weight.</p>
<p>The new study set out to determine whether the various hyperdense patterns seen at entry sites represent a single phenomenon or a heterogeneous spectrum. Led by Radiya Sri Rajendran, with Stephan Andreas Bolliger, Michael Josef Thali, and Dominic Gascho as co-authors, the team analyzed fifty cases of gunshot wounds to the head and neck, all considered consistent with short-range shots based on forensic documentation. Thirty-five cases, seventy percent, were through-and-through injuries with an exit wound, while fifteen cases, thirty percent, involved retained projectiles. Pistols accounted for sixty-six percent of the weapons, revolvers for twenty-six percent, and rifles for eight percent, with 9 mm Para and .22 long rifle ammunition the most frequently represented calibers.</p>
<p>Imaging was performed on a 128-slice SOMATOM Definition Flash scanner using standardized parameters: a tube voltage of 120 kV, a tube current-time product of 400 mAs, a pitch of 0.35, and a rotation time of 1.0 second. Datasets were reconstructed at a slice thickness of 0.6 millimeters with a bone kernel to optimize visualization of radiopaque structures. Two readers with very different levels of experience independently assessed gunshot residue-related hyperdensities: Reader 1 was a physician without specific training in forensic radiology or wound ballistics, while Reader 2 was a forensic imaging specialist with thirteen years of experience. Other findings—bone fragments, fracture lines, projectile fragments, and the radiopaque ring sign—were evaluated by consensus. Agreement on residue detection was moderate, with a Cohen&#8217;s kappa of 0.55, a figure that itself underscores how difficult these distinctions can be.</p>
<p>The results paint a picture of considerable morphological complexity. Gunshot residue-related hyperdensities were identified in eighty-two percent of cases by the less experienced reader and seventy-two percent by the specialist, with discrepancies concentrated in cases where residue patterns were limited or diffuse. Bone fragments were the most consistent radiopaque finding at the entry site, present in the vast majority of cases, and their radiodensity frequently overlapped with that of residue, complicating differentiation. Projectile fragments, by contrast, could be reliably separated from both because of their markedly higher radiodensity—often reaching the upper measurable limit of the Hounsfield unit scale at 3071 HU—and the characteristic streak artifacts they produce. Residue itself exhibited a wide range of maximum attenuation values, from 550 to 3022 HU with a median of 1705.5, reflecting focal high-density components rather than the overall composition of the deposit.</p>
<p>Against this backdrop of ambiguity, the radiopaque ring sign stood out. In the three cases where it appeared, it manifested as a compact, continuous circumferential structure embedded within the subcutaneous tissue at the wound margin, clearly distinguishable from both diffuse hyperdensities and focal metallic fragments. Two of the three cases involved a revolver firing .22 long rifle ammunition, and the third involved a revolver chambered in .38 S&amp;W. Critically, in cases with through-and-through injuries, no comparable ring-like structure was observed at the exit sites, even though those sites also contained a mixture of bone and projectile fragments. This asymmetry supports the interpretation that the ring sign is a specific phenomenon of the entry site rather than a general accumulation of radiopaque material, and all three ring-sign cases showed external findings clearly attributable to contact gunshot wounds.</p>
<p>The distinction matters because the forensic literature has not always separated these patterns. Early work by Stein and colleagues in 2000 illustrated gunshot residue findings on PMCT, including a ring-like accumulation reproduced experimentally in a porcine model, but did not consistently treat it as a separate entity. Later studies described residue as spontaneously dense material around entrance wounds in intermediate-range shots, implying more diffuse or surface-related patterns. Gascho and colleagues explicitly reported a subdermal ring of radiopaque material at the entry wound of neck injuries from a contact shot, and porcine cadaver experiments by Junno and colleagues in 2022 reinforced the reproducibility of a ring-shaped structure particularly in contact shots, pointing to a distance-dependent mechanism. More recently, Jupin-Delevaux and colleagues introduced the hyperdense rim sign as a marker for entry wound identification, but their definition rests largely on geometric criteria and may encompass both compact rings and ill-defined perilesional hyperdensities under a single term.</p>
<p>The Zurich team argues that this broader usage risks overgeneralization. Their data indicate that superficial hyperdensities at the wound margin, diffuse perilesional deposits within surrounding tissue, and the compact radiopaque ring sign likely reflect distinct underlying mechanisms. The diffuse patterns probably correspond to surface contamination and combustion-related effects, whereas the ring may arise from a more localized deposition process under specific ballistic conditions—possibly related to gases and particulates forced into the subcutaneous tissue when the muzzle is pressed against the skin. The authors also note that Hounsfield unit measurements alone cannot resolve the question, since maximum attenuation values are dominated by metallic fragments and partial volume effects, and they found that three-dimensional visualization techniques such as cinematic rendering helped in selected cases by clarifying the shape and spatial distribution of ambiguous structures.</p>
<p>The study&#8217;s implications extend to an open question in classical forensic pathology: whether the radiopaque ring on PMCT relates to the contusion ring seen on external examination of the skin. The authors suggest that prospective or experimental studies with standardized documentation of both external and radiological findings, ideally combined with histopathological analysis, could clarify whether the two phenomena are connected or independent. They also acknowledge limitations: the retrospective design and restriction to head and neck wounds limit generalizability to other anatomical regions; reliable discrimination among contact, near-contact, and close-range shots was not possible in every case due to tissue destruction, decomposition, or inconclusive external findings; and the subgroup of ring-sign cases is small. The imaging data themselves, containing identifiable anatomical features, are not publicly available, though they may be accessible from the corresponding author under institutional and ethical approval.</p>
<p>Even with those caveats, the message for forensic practice is clear. Hyperdense findings at the wound margin are common on PMCT and remain valuable for identifying entry wounds, but they should not be read as a single entity. A true radiopaque ring sign is rare, morphologically distinct, confined to the entry site, and in this cohort appeared only in contact shots, whereas other residue-related hyperdensities occur across a broader range of firing distances and demand cautious, context-informed interpretation. As virtual autopsy techniques continue to spread through forensic institutes worldwide, refining the vocabulary and diagnostic criteria for what appears on the scan could mean the difference between an ambiguous finding and decisive evidence.</p>
<p><strong>Subject of Research:</strong> Radiopaque ring sign at gunshot wound entry sites on postmortem CT</p>
<p><strong>Article Title:</strong> Radiopaque ring sign as a distinct finding at the entry site of gunshot wounds on postmortem CT</p>
<p><strong>Article References:</strong> Rajendran, R. S., Bolliger, S. A., Thali, M. J., &amp; Gascho, D. (2026). Radiopaque ring sign as a distinct finding at the entry site of gunshot wounds on postmortem CT. <em>International Journal of Legal Medicine</em>. <a href="https://doi.org/10.1007/s00414-026-04004-8" rel="noopener noreferrer">https://doi.org/10.1007/s00414-026-04004-8</a></p>
<p><strong>Image Credits:</strong> AI Generated</p>
<p><strong>DOI:</strong> <a href="https://doi.org/10.1007/s00414-026-04004-8" rel="noopener noreferrer">10.1007/s00414-026-04004-8</a></p>
<p><strong>Keywords:</strong> gunshot residue, postmortem CT, radiopaque ring sign, forensic imaging, virtual autopsy, wound ballistics, entry wound, hyperdense rim sign, contact shot, forensic radiology, Radiopaque, ring</p>
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		<post-id xmlns="com-wordpress:feed-additions:1">196919</post-id>	</item>
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