<?xml version="1.0" encoding="UTF-8"?><rss version="2.0"
	xmlns:content="http://purl.org/rss/1.0/modules/content/"
	xmlns:wfw="http://wellformedweb.org/CommentAPI/"
	xmlns:dc="http://purl.org/dc/elements/1.1/"
	xmlns:atom="http://www.w3.org/2005/Atom"
	xmlns:sy="http://purl.org/rss/1.0/modules/syndication/"
	xmlns:slash="http://purl.org/rss/1.0/modules/slash/"
	>

<channel>
	<title>Colorado &#8211; Science</title>
	<atom:link href="https://scienmag.com/tag/colorado/feed/" rel="self" type="application/rss+xml" />
	<link>https://scienmag.com</link>
	<description></description>
	<lastBuildDate>Thu, 08 Oct 2026 19:44:14 +0000</lastBuildDate>
	<language>en-US</language>
	<sy:updatePeriod>
	hourly	</sy:updatePeriod>
	<sy:updateFrequency>
	1	</sy:updateFrequency>
	<generator>https://wordpress.org/?v=7.1.3</generator>

<image>
	<url>https://scienmag.com/wp-content/uploads/2024/07/cropped-scienmag_ico-32x32.jpg</url>
	<title>Colorado &#8211; Science</title>
	<link>https://scienmag.com</link>
	<width>32</width>
	<height>32</height>
</image> 
<site xmlns="com-wordpress:feed-additions:1">73899611</site>	<item>
		<title>Cosmic Rain: Colorado Soils Reveal How Millions of Beryllium-10 Atoms Fall Each Year</title>
		<link>https://scienmag.com/cosmic-rain-colorado-soils-reveal-how-millions-of-beryllium-10-atoms-fall-each-year/</link>
		
		<dc:creator><![CDATA[Violet Maxwell]]></dc:creator>
		<pubDate>Thu, 08 Oct 2026 19:44:14 +0000</pubDate>
				<category><![CDATA[Earth Science]]></category>
		<category><![CDATA[accelerator mass spectrometry]]></category>
		<category><![CDATA[beryllium-10]]></category>
		<category><![CDATA[calibration of beryllium-10 deposition rates]]></category>
		<category><![CDATA[Colorado]]></category>
		<category><![CDATA[cosmic fallout for geological dating]]></category>
		<category><![CDATA[cosmic ray-induced beryllium-10]]></category>
		<category><![CDATA[cosmogenic nuclides]]></category>
		<category><![CDATA[East River watershed]]></category>
		<category><![CDATA[erosion measurement using beryllium-10]]></category>
		<category><![CDATA[erosion rates]]></category>
		<category><![CDATA[geochronology]]></category>
		<category><![CDATA[geochronology and landscape evolution]]></category>
		<category><![CDATA[glacial moraines]]></category>
		<category><![CDATA[glacial soils in Colorado Rockies]]></category>
		<category><![CDATA[high-energy cosmic rays and atmospheric interactions]]></category>
		<category><![CDATA[implications for geological and environmental studies]]></category>
		<category><![CDATA[influence of elevation and snowfall on isotope deposition]]></category>
		<category><![CDATA[orographic precipitation]]></category>
		<category><![CDATA[sediment tracing in river basins]]></category>
		<category><![CDATA[snow water equivalent]]></category>
		<category><![CDATA[soil chemistry effects on beryllium-10 accumulation]]></category>
		<category><![CDATA[soil inventories]]></category>
		<category><![CDATA[soil isotope analysis]]></category>
		<category><![CDATA[watershed science]]></category>
		<guid isPermaLink="false">https://scienmag.com/?p=248929</guid>

					<description><![CDATA[Measurements of cosmic beryllium-10 in glacial soils across a Colorado watershed reveal that millions of atoms fall on each square centimeter yearly, with delivery rates rising with elevation and snowfall and enabling new maps for measuring erosion.]]></description>
										<content:encoded><![CDATA[<p>Every second, high-energy cosmic rays slam into the atmosphere, shattering nitrogen and oxygen atoms and forging rare isotopes that rain quietly onto the landscape below. Among them is beryllium-10, a radioactive atom that clings stubbornly to soil particles once it reaches the ground. For decades, geologists have exploited this cosmic fallout as a clock and a tracer, using it to date landforms, measure erosion, and follow sediment through river basins. But the method has an Achilles heel: nobody knows precisely how fast beryllium-10 falls at any given place. A new study of glacial soils in the Colorado Rockies now delivers one of the most detailed local calibrations ever attempted, revealing that millions of these atoms blanket every square centimeter of mountain terrain each year, and that the rate shifts dramatically with elevation, snowfall, and even the chemistry of the soil itself.</p>
<p>The research, published in the journal Geochronology, was led by José M. Marmolejo-Cossío and Isaac J. Larsen of the University of Massachusetts Amherst, together with Eyal Marder and Alan J. Hidy of Lawrence Livermore National Laboratory. The team focused on the East River watershed near Crested Butte, Colorado, a steep alpine catchment draining the Elk Range of the Rocky Mountains and feeding the Gunnison River, a major tributary of the Colorado. Elevations in the watershed span roughly 2,600 to 4,100 meters, mean annual temperature hovers near zero degrees Celsius, and most precipitation arrives as snow that can pile up several meters deep. Crucially, the bedrock is dominated by Cretaceous Mancos Shale, a quartz-poor rock that thwarts the standard method of measuring erosion with beryllium-10 produced inside mineral grains. That limitation makes the watershed an ideal proving ground for the meteoric variety of the isotope, which can be measured in almost any soil regardless of quartz content.</p>
<p>The researchers&#8217; strategy hinged on a gift from the last ice age. Between roughly 18,000 and 13,000 years ago, Pleistocene glaciers carved cirques into the high peaks and dumped moraines, ridges of glacial debris, across the valley floors. Because previous work had independently dated five of these moraines using in situ-produced beryllium-10 in boulders, the team knew exactly how long each land surface had been exposed to the sky. By digging soil pits into the flattest crests of the moraines, sampling in depth increments down to 145 centimeters, and measuring the total inventory of meteoric beryllium-10 in each profile, they could divide the accumulated atoms by the landform age to recover a millennial-averaged delivery rate. The approach assumes the clock started when the ice retreated, and the team carefully corrected for inherited atoms that had stuck to mineral grains before the sediments were deposited.</p>
<p>The laboratory work was formidable. Roughly half a gram of powdered soil from each depth interval was fused with fluxes in platinum crucibles, spiked with a known quantity of stable beryllium-9, and chemically purified through repeated dissolution and precipitation steps. The resulting beryllium oxide was packed into cathodes and analyzed by accelerator mass spectrometry at Lawrence Livermore, where 10Be/9Be ratios on the order of 10^-12 were measured against calibrated standards, with process blanks several orders of magnitude lower. The team also measured soil pH in water and calcium chloride solutions, because beryllium retention in soils depends strongly on acidity: soils with pH above roughly 4 hold onto the isotope, while more acidic profiles can leach it away. Natural beryllium-9 in the samples turned out to be negligible compared with the added carrier, simplifying the interpretation.</p>
<p>The results are striking. Inheritance-corrected inventories ranged from 7.68 billion to 23.5 billion atoms per square centimeter, and the corresponding fluxes ranged from about 430,000 to 1.8 million atoms per square centimeter per year across the five sites. When the researchers additionally modeled losses from erosion and from desorption, the chemical detachment of beryllium from mineral surfaces and its downward migration in soil water, corrected fluxes spanned 310,000 to 3.7 million atoms per square centimeter per year, deviating from the uncorrected values by factors of 0.3 to 2.1. Desorption losses were predicted to be greatest at the highest, most acidic Copper Creek site, where modeled losses ran an order of magnitude above those at the other moraines, while erosional losses peaked at the most topographically convex Gothic moraine.</p>
<p>Perhaps the most consequential finding is how tightly the flux tracks the mountain environment. Inheritance-corrected fluxes correlated with elevation with an R-squared of 0.91, with mean annual precipitation at 0.82 to 0.85, with mean snow depth at 0.95 to 0.97, and with snow water equivalent at 0.97 to 0.98. The reason is orography: within the East River watershed, precipitation increases with elevation as moist air is forced upslope, so the cosmic isotope rains down faster on the high country than on the valley floor. By applying these regression equations to high-resolution gridded datasets, including 3-meter LiDAR elevation models, downscaled PRISM precipitation data, and Airborne Snow Observatory maps of snow depth and snow water equivalent, the team produced the first spatially resolved maps of beryllium-10 flux for an entire mountain watershed, with watershed-averaged predictions of 1.1 to 3.8 million atoms per square centimeter per year depending on the predictor chosen.</p>
<p>The snow-based maps revealed a subtle topographic fingerprint that precipitation averages alone would miss. Because wind and avalanches strip snow from sharp ridge crests and pile it on adjacent slopes, the models predict lower beryllium-10 accumulation on ridgelines than on nearby hillsides. Yet the snow data also carry risks: they cover only two winters, a vanishingly small slice of the roughly 15,000 years over which the soils have collected the isotope, and some of the deepest snow measurements in the watershed, exceeding 20 meters, are likely measurement artifacts. Elevation, by contrast, is the only predictor immune to temporal bias, though it too can mislead where local topography redistributes snow. The authors suggest that, much like exposure-age analysts who average results from multiple production-rate scaling models, future users of meteoric beryllium-10 may need to adopt an ensemble approach that weighs all of these predictors.</p>
<p>The comparison with existing models was sobering. A widely used empirical model that predicts flux as a function of precipitation and latitude overestimated the measured fluxes by factors of 1.8 to 3.8 relative to inheritance-corrected values, and by 1.0 to 6.0 relative to erosion- and desorption-corrected values. Global circulation models, which simulate atmospheric production and transport of the isotope, fared better at the watershed scale: their predictions of roughly 1.46 to 2.12 million atoms per square centimeter per year generally fell within the range of the locally calibrated watershed averages. But a single grid cell in these global models covers an area larger than the entire watershed, so they completely miss the within-basin variability driven by orographic precipitation. At the site scale, the highest model-based prediction exceeded the lowest corrected field flux by a factor of 7 to 13.</p>
<p>The East River fluxes also fit into a broader regional picture. Soil-inventory-based estimates from the wetter Colorado Front Range and the drier Wind River Mountains of Wyoming cluster around 1.3 to 1.5 million atoms per square centimeter per year, and the East River values of 0.43 to 1.8 million are broadly consistent, with the driest site in the study falling below the regional norms. One complication the authors flag is dust: windblown particles carry beryllium-10 that was scavenged elsewhere, potentially contributing up to about 20 percent of the total flux in some settings. In the Colorado Front Range, dust is thought to contribute less than 10 percent, and if East River conditions are similar, the discrepancy with global models would not change substantially, though the dust contribution there remains unconstrained.</p>
<p>The practical payoff could be considerable. Because meteoric beryllium-10 can be measured in quartz-poor shales and paired with stable beryllium-9 to estimate catchment-wide denudation and chemical weathering, a locally calibrated flux transforms the East River watershed, already an intensive Department of Energy research site for watershed science, into a place where erosion and weathering rates can be quantified across shale terrain that the standard method cannot touch. More broadly, the study demonstrates a template for other alpine landscapes: combine independently dated landforms, careful soil chemistry, and modern high-resolution LiDAR and snowpack datasets to turn a global cosmic drizzle into a locally predictable tool. The atoms fall from the sky whether we measure them or not; this work shows how to read them accurately.</p>
<p><strong>Subject of Research:</strong> Measurement of meteoric beryllium-10 deposition fluxes from soil inventories on glacial moraines in the East River watershed, Colorado</p>
<p><strong>Article Title:</strong> Meteoric beryllium-10 fluxes from soil inventory measurements in the East River watershed, Colorado, USA</p>
<p><strong>Article References:</strong> Marmolejo-Cossío, J. M., Larsen, I. J., Marder, E., &amp; Hidy, A. J. (2026). Meteoric beryllium-10 fluxes from soil inventory measurements in the East River watershed, Colorado, USA. <em>Geochronology, 8</em>(3), 547-565. <a href="https://doi.org/10.5194/gchron-8-547-2026" rel="noopener noreferrer">https://doi.org/10.5194/gchron-8-547-2026</a></p>
<p><strong>Image Credits:</strong> AI Generated</p>
<p><strong>DOI:</strong> <a href="https://doi.org/10.5194/gchron-8-547-2026" rel="noopener noreferrer">10.5194/gchron-8-547-2026</a></p>
<p><strong>Keywords:</strong> beryllium-10, cosmogenic nuclides, glacial moraines, soil inventories, erosion rates, East River watershed, Colorado, orographic precipitation, geochronology, accelerator mass spectrometry, snow water equivalent, watershed science</p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">248929</post-id>	</item>
		<item>
		<title>Colorado Bets $4.9 Million on Rural Pharmacies to Close Its Widening Healthcare Gap</title>
		<link>https://scienmag.com/colorado-bets-4-9-million-on-rural-pharmacies-to-close-its-widening-healthcare-gap/</link>
		
		<dc:creator><![CDATA[Ophelia Keating]]></dc:creator>
		<pubDate>Tue, 06 Oct 2026 04:08:12 +0000</pubDate>
				<category><![CDATA[Medicine]]></category>
		<category><![CDATA[chronic disease]]></category>
		<category><![CDATA[CMS]]></category>
		<category><![CDATA[Colorado]]></category>
		<category><![CDATA[Colorado Rural Health Transformation Program]]></category>
		<category><![CDATA[Colorado rural pharmacy investment]]></category>
		<category><![CDATA[Colorado STREAM healthcare project]]></category>
		<category><![CDATA[community pharmacists in healthcare]]></category>
		<category><![CDATA[community pharmacy]]></category>
		<category><![CDATA[community-based healthcare collaboration]]></category>
		<category><![CDATA[cost-effective rural healthcare solutions]]></category>
		<category><![CDATA[CU Anschutz]]></category>
		<category><![CDATA[federally funded rural health programs]]></category>
		<category><![CDATA[healthcare gap in frontier communities]]></category>
		<category><![CDATA[healthcare workforce]]></category>
		<category><![CDATA[hub-and-spoke model]]></category>
		<category><![CDATA[long-term rural health investment]]></category>
		<category><![CDATA[medication management]]></category>
		<category><![CDATA[opioid use disorder]]></category>
		<category><![CDATA[rural health]]></category>
		<category><![CDATA[Rural Health Transformation Program]]></category>
		<category><![CDATA[rural healthcare access initiatives]]></category>
		<category><![CDATA[rural healthcare innovation]]></category>
		<category><![CDATA[telehealth]]></category>
		<category><![CDATA[telepharmacy and rural health]]></category>
		<guid isPermaLink="false">https://scienmag.com/?p=240170</guid>

					<description><![CDATA[A $4.94 million first-year federal award launches Colorado STREAM, a five-year, nearly $25 million initiative connecting rural pharmacies with treatment hubs and telehealth to expand healthcare access across the state's rural and frontier counties.]]></description>
										<content:encoded><![CDATA[<p>A sweeping new experiment in American rural healthcare is about to unfold across the mountains, plains and frontier counties of Colorado, and its central players will not be hospitals or newly recruited physicians, but the community pharmacists already standing behind counters in nearly every small town in the state. The CU Anschutz Skaggs School of Pharmacy and Pharmaceutical Sciences has joined a statewide, community-based collaborative led by Denver Recovery Group that has received a $4.94 million first-year award through Colorado&#8217;s Rural Health Transformation Program, a federally backed initiative administered by the Colorado Department of Health Care Policy &amp; Financing. The funding launches Colorado STREAM, a five-year initiative designed to bring coordinated, whole-person healthcare closer to people living in rural and frontier communities, where the nearest treatment center or specialist can sit hours away down a two-lane highway.</p>
<p>If annual funding is approved at the first-year level, the initiative represents nearly $25 million in investment in rural Colorado over five years. Approximately $1.42 million of the first-year award is budgeted to support CU Anschutz Pharmacy&#8217;s role in the project, an investment that could total more than $7 million over the full five-year span, making STREAM one of the largest awards in the history of the Skaggs School. Denver Recovery Group serves as the lead grantee, working in partnership with CU Anschutz Pharmacy, The Steadman Group, and community and healthcare partners across the state to develop and implement the new model. The scale of the collaboration reflects a deliberate design choice: rather than building new infrastructure from scratch, STREAM aims to connect the healthcare resources and trusted relationships that already exist in Colorado&#8217;s small communities into a single coordinated network of care.</p>
<p>The scale of the problem the initiative confronts is stark. Nearly 722,000 Coloradans live in rural communities, and 47 of the state&#8217;s 64 counties are classified as rural or frontier. Many residents face chronic healthcare provider shortages, long travel distances and limited access to specialty and behavioral health services. Those barriers become particularly consequential for people seeking treatment for opioid use disorder, a condition for which rural communities often have few treatment providers and limited behavioral health resources, and where transportation difficulties and fragmented care can make it hard for patients to begin and remain in treatment. At the same time, rural populations carry significant burdens from chronic conditions such as diabetes, hypertension and cardiovascular disease, illnesses that demand consistent monitoring, careful medication management and ongoing clinical follow-up that distant clinics struggle to provide.</p>
<p>Colorado STREAM&#8217;s answer to this geography of scarcity is a hub-and-spoke architecture built around the local pharmacy. The model will create connections among regional treatment hubs, community pharmacy networks, telehealth services and coordinated whole-person care. Concretely, the initiative will work to expand access to evidence-based medications and support for opioid use disorder; connect patients and rural pharmacy teams with treatment specialists and other clinicians through telehealth and coordinated referrals; increase access to medication management for chronic diseases such as diabetes, hypertension and cardiovascular disease; and build rural healthcare workforce capacity by training pharmacists, pharmacy technicians, students, preceptors and collaborating healthcare professionals. The program will also develop sustainable models that allow community pharmacies to play a larger role in delivering and coordinating healthcare, and it will use data and evaluation to measure outcomes, improve care and refine a model that can be sustained and expanded over time.</p>
<p>The logic of placing pharmacies at the center of the network is grounded in both trust and logistics. Community pharmacists are among the most accessible healthcare professionals in rural America, often the only clinically trained providers physically present in a town, and they already hold medication expertise and established relationships with the patients they serve. By connecting them with treatment specialists, technology and coordinated care networks, the initiative aims to bring critical services closer to patients rather than asking patients to travel long distances to find care. Telehealth links and structured referral pathways are intended to extend the reach of regional treatment centers into communities where recruiting physicians and behavioral health clinicians has proven persistently difficult, converting existing pharmacy counters into access points for a far broader continuum of care.</p>
<p>The partnership behind the project is deliberately broad. Denver Recovery Group, led on the ground by Regional Director Denise Vincioni, served as the lead applicant and brings evidence-based treatment expertise for opioid use disorder, including medications for opioid use disorder, counseling, case management and care coordination. The Steadman Group, led on the project by JK Costello, MD, MPH, contributes program design and evaluation capacity, while the CU Anschutz team, led by Rob Valuck, PhD, RPh, Wes Nuffer, PharmD, and Dean Brian Tsuji, PharmD, adds academic depth in pharmacy practice, addiction science and experiential training. The collaboration also includes national and regional pharmacy operators Albertsons-Safeway and Kroger/City Market, independent rural pharmacies such as Downtown Drug in Glenwood Springs and Buena Vista Drug, and CPESN Colorado, a statewide network focused on expanding community pharmacy-based patient care. Emily Zadvorny, PharmD, Executive Director of the Colorado Pharmacists Society, brings additional statewide pharmacy leadership to the effort, a roster designed to ensure the model is informed by the realities of delivering care in communities of very different sizes and regions.</p>
<p>Leaders involved in the project have framed it as a rethinking of how healthcare can reach places the traditional system has left behind. Dean Brian Tsuji has described the investment as an extraordinary opportunity to rethink rural care delivery, noting that community pharmacists are already trusted professionals embedded in these communities and that connecting them with treatment specialists, technology and coordinated networks can bring services to patients instead of forcing patients toward services. Denise Vincioni has emphasized that people in rural Colorado should be able to receive high-quality treatment and coordinated healthcare closer to home, and that STREAM connects treatment expertise with trusted community pharmacies, academic partners, technology and local care resources so that distance is less of a barrier to recovery and better health. Rob Valuck has argued that where a person lives should not determine whether they can get the care they need, and that the strength of the hub-and-spoke model lies in not trying to recreate an entire healthcare system in every rural community, but in connecting regional expertise with pharmacists already caring for patients close to home.</p>
<p>Wes Nuffer has added a practical dimension to that vision, observing that for many rural Coloradans the community pharmacy may be one of the most accessible points of healthcare in their community, and that STREAM builds on that existing relationship rather than creating entirely new infrastructure. From the university&#8217;s perspective, the initiative also carries an educational mission: preparing future pharmacists to practice in rural and frontier settings and demonstrating how pharmacists can contribute more broadly to the healthcare team. Tsuji has noted that pharmacists have always been medication experts but that their potential contribution to rural healthcare extends much further, and that STREAM offers a chance both to improve access today and to train the next generation of pharmacists to become an integral part of the rural healthcare workforce, a tangible example of combining education, innovation, clinical expertise and community partnerships to tackle complex healthcare challenges.</p>
<p>The award sits within a much larger wave of federal investment. Colorado&#8217;s Rural Health Transformation Program is supported through the federal Rural Health Transformation Program administered by the Centers for Medicare &amp; Medicaid Services, a five-year initiative authorized under Section 71401 of H.R. 1, Public Law 119-21, which provides grants totaling $50 billion in federal funding nationwide from Federal Fiscal Year 2026 through FFY 2030. Colorado is directing $169,587,181 in RHTP grants to rural healthcare providers across the state, and through a highly competitive application process, 91 applicants and approximately 250 projects were selected to receive funding across 52 rural or frontier counties and three rural census tract counties. Colorado&#8217;s first-year award totals $200,105,604.17 and is 100 percent funded by CMS. The state program&#8217;s priorities include expanding the rural healthcare workforce, strengthening rural healthcare networks, increasing preventive care capacity, integrating telehealth and technology, and developing new approaches to rural care delivery, priorities that STREAM touches on nearly every front.</p>
<p>For the communities involved, the measure of success will be practical: whether a person with opioid use disorder in a frontier county can start evidence-based medication without a multi-hour drive, whether a diabetic patient can get consistent medication management from a pharmacist they already know, and whether the network can sustain itself financially beyond the grant period. The award remains subject to execution of the Grant Agreement and annual funding is subject to continued approval, so the five-year horizon is not yet guaranteed. But if the model performs as its architects hope, Colorado STREAM could offer a template for a national question: how to convert the most trusted and most accessible healthcare professionals in rural America into the connective tissue of a system that has long struggled to reach them. The initiative&#8217;s own data and evaluation work will determine whether that template is ready to travel beyond the Rockies.</p>
<p><strong>Subject of Research:</strong> Pharmacy-based rural healthcare access and opioid use disorder treatment in Colorado through the Rural Health Transformation Program</p>
<p><strong>Article Title:</strong> $4.9M RHTP award will expand pharmacy-based healthcare access across rural Colorado</p>
<p><strong>Article References:</strong> $4.9M RHTP award will expand pharmacy-based healthcare access across rural Colorado. (n.d.). <a href="https://www.eurekalert.org/news-releases/1146578" rel="noopener noreferrer">Original publication</a></p>
<p><strong>Image Credits:</strong> AI Generated</p>
<p><strong>DOI:</strong> Not provided</p>
<p><strong>Keywords:</strong> rural health, community pharmacy, opioid use disorder, telehealth, Colorado, Rural Health Transformation Program, CU Anschutz, medication management, hub-and-spoke model, healthcare workforce, chronic disease, CMS</p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">240170</post-id>	</item>
		<item>
		<title>Cannabis Use Disorder Linked to 52 Percent Higher Death Risk in Large Colorado Cohort</title>
		<link>https://scienmag.com/cannabis-use-disorder-linked-to-52-percent-higher-death-risk-in-large-colorado-cohort/</link>
		
		<dc:creator><![CDATA[Phoebe Ingram]]></dc:creator>
		<pubDate>Thu, 01 Oct 2026 12:08:11 +0000</pubDate>
				<category><![CDATA[Medicine]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[cannabis use disorder]]></category>
		<category><![CDATA[cannabis use disorder and overdose deaths]]></category>
		<category><![CDATA[cannabis use disorder in Colorado population]]></category>
		<category><![CDATA[cannabis use disorder long-term mortality risk]]></category>
		<category><![CDATA[clinical implications of cannabis use disorder]]></category>
		<category><![CDATA[Colorado]]></category>
		<category><![CDATA[Cox proportional hazards]]></category>
		<category><![CDATA[drug overdose]]></category>
		<category><![CDATA[drug overdose and accidents in cannabis users]]></category>
		<category><![CDATA[epidemiology]]></category>
		<category><![CDATA[epidemiology of cannabis use disorder]]></category>
		<category><![CDATA[health outcomes of cannabis dependence]]></category>
		<category><![CDATA[health records analysis of cannabis use disorder]]></category>
		<category><![CDATA[impact of cannabis use disorder on cancer risk]]></category>
		<category><![CDATA[injury-related death]]></category>
		<category><![CDATA[Journal of General Internal Medicine]]></category>
		<category><![CDATA[long-term health effects of cannabis dependence]]></category>
		<category><![CDATA[matched cohort study]]></category>
		<category><![CDATA[mortality]]></category>
		<category><![CDATA[mortality comparison between cannabis users and non-users]]></category>
		<category><![CDATA[Public health]]></category>
		<category><![CDATA[risks associated with impaired control over cannabis use]]></category>
		<category><![CDATA[substance use]]></category>
		<guid isPermaLink="false">https://scienmag.com/?p=222538</guid>

					<description><![CDATA[A matched cohort study of over 100,000 Colorado health system patients found that cannabis use disorder was associated with a 52 percent higher risk of all-cause mortality, driven by elevated deaths from drug overdose, accidents, and cancer.]]></description>
										<content:encoded><![CDATA[<p>A sweeping new study drawing on nearly two decades of health records has found that people diagnosed with cannabis use disorder die at substantially higher rates than comparable patients without the diagnosis, with the excess driven largely by drug overdose, accidents, and cancer. The research, published in the Journal of General Internal Medicine, followed more than 100,000 individuals cared for within a Colorado health system between 2006 and 2024 and offers one of the most detailed pictures yet of how a condition that often goes unrecognized in clinical practice shapes long-term survival.</p>
<p>The study team, led by Anh P. Nguyen of the Institute for Health Research at Kaiser Permanente Colorado, assembled a matched cohort of 100,140 people aged 12 years or older. Of these, 16,693 had received a diagnosis of cannabis use disorder, a clinical condition marked by impaired control over cannabis use, continued use despite harmful consequences, and physiological dependence in some patients. Each person with the disorder was compared against individuals without the diagnosis drawn from the same health system, allowing the researchers to isolate the association between the condition and mortality while accounting for shared characteristics of the patient population.</p>
<p>Follow-up extended through June 2024, with a median observation period of 7.7 years. Death records came from state vital statistics, enabling the team to classify not only whether people died but why. Over the follow-up window, 1,197 individuals with cannabis use disorder died, representing 7.2 percent of that group. The raw numbers were stark: people with the disorder died at a crude rate of 899.5 per 100,000 person-years, compared with 374.6 per 100,000 person-years among matched individuals without the diagnosis, a difference of more than a factor of two before any statistical adjustment.</p>
<p>Because people with substance use disorders often carry other health and social burdens, the investigators used Cox proportional hazards regression to adjust for confounding factors and estimate adjusted hazard ratios. Even after this statistical correction, the signal remained strong. Cannabis use disorder was associated with a 52 percent higher risk of death from any cause, with an adjusted hazard ratio of 1.52 and a 95 percent confidence interval of 1.30 to 1.77. The confidence interval excludes the null value of 1.0, indicating that the association is unlikely to be explained by random variation in the data.</p>
<p>The researchers then split deaths into two broad categories: injury-related and illness-related. Injury deaths, which include overdoses, accidents, and self-harm, occurred at a crude rate of 295.3 per 100,000 person-years among people with cannabis use disorder versus 62.5 among matched comparators, nearly a fivefold difference in unadjusted rates. After adjustment, the disorder was associated with a 91 percent higher risk of injury-related death, with a hazard ratio of 1.91 and a confidence interval of 1.37 to 2.67. Illness-related mortality, covering deaths from disease, was also elevated, at 604.2 versus 312.1 per 100,000 person-years in crude terms, with an adjusted hazard ratio of 1.40.</p>
<p>Drilling down into specific causes of death revealed a differentiated pattern. The strongest association was with drug overdose: people with cannabis use disorder had nearly 2.6 times the risk of dying from an overdose, with a hazard ratio of 2.59 and a confidence interval of 1.30 to 5.19. This finding aligns with a growing body of evidence that cannabis use disorder frequently co-occurs with other substance use disorders, and that polysubstance use multiplies overdose danger. Deaths from accidents were also significantly elevated, with a hazard ratio of 1.96, consistent with concerns about impairment-related injuries in an era of expanding cannabis availability.</p>
<p>Cancer mortality emerged as another significant contributor, with an adjusted hazard ratio of 1.71 and a confidence interval of 1.20 to 2.46. The authors and related literature note that cannabis is most commonly consumed by smoking, and recent observational studies have begun to examine links between cannabis smoking and lung cancer as well as broader cancer risk in the context of legalized access. By contrast, the study found no statistically significant elevation in deaths from self-harm, cardiovascular disease, or respiratory disease. The hazard ratios for those causes were 1.18, 1.25, and 1.29 respectively, but all of their confidence intervals crossed 1.0, meaning the data could not distinguish those estimates from no increased risk.</p>
<p>The findings arrive at a moment of rapid change in the American cannabis landscape. Self-reported cannabis use in the United States has risen markedly over recent decades, and prior research has documented increases in cannabis use disorder following recreational legalization in several states. National surveys have also shown that the prevalence of marijuana use disorders grew substantially between the early 2000s and the early 2010s. Yet cannabis use disorder remains underrecognized in routine care, and evidence on mortality among affected individuals has historically been limited, often relying on treatment-seeking populations or emergency department cohorts rather than broad health-system samples.</p>
<p>The new study adds to a small but growing literature. A 2025 analysis published in JAMA Network Open linked cannabis use disorder-related emergency department visits and hospitalizations to elevated five-year mortality, and a 2025 systematic review and meta-analysis of cohort studies reported increased all-cause mortality associated with cannabis use. The Colorado cohort strengthens this evidence base by using matched comparison individuals from the same integrated health system, by capturing deaths through official vital records rather than electronic health data alone, and by distinguishing injury-related from illness-related causes of death within a single analytic framework.</p>
<p>The authors caution that the study is observational: it identifies associations, not proof of causation, and cannabis use disorder may act partly as a marker for a constellation of risks, including co-occurring substance use, mental health conditions, and social determinants of health that themselves predict premature death. Still, the researchers conclude that a diagnosis of cannabis use disorder may serve as a clinically meaningful signal of elevated all-cause, injury-related, and illness-related mortality risk, and they call for comprehensive prevention strategies to address the heightened risk in this population. As cannabis potency and availability continue to climb, the study suggests that identifying and treating cannabis use disorder in primary care settings could become an increasingly important piece of the mortality-prevention puzzle.</p>
<p><strong>Subject of Research:</strong> Mortality risk associated with cannabis use disorder in a matched Colorado health system cohort</p>
<p><strong>Article Title:</strong> Cannabis Use Disorder and Mortality Risk: A Matched Cohort Study from a Colorado Health System</p>
<p><strong>Article References:</strong> Cannabis Use Disorder and Mortality Risk: A Matched Cohort Study from a Colorado Health System. (n.d.). <a href="https://doi.org/10.1007/s11606-026-10845-1" rel="noopener noreferrer">https://doi.org/10.1007/s11606-026-10845-1</a></p>
<p><strong>Image Credits:</strong> AI Generated</p>
<p><strong>DOI:</strong> <a href="https://doi.org/10.1007/s11606-026-10845-1" rel="noopener noreferrer">10.1007/s11606-026-10845-1</a></p>
<p><strong>Keywords:</strong> cannabis use disorder, mortality, matched cohort study, drug overdose, cancer, injury-related death, Cox proportional hazards, Colorado, public health, substance use, epidemiology, Journal of General Internal Medicine</p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">222538</post-id>	</item>
		<item>
		<title>Male Dogs and the Very Young and Old Face Higher Risk of Severe Bites, Colorado Study Finds</title>
		<link>https://scienmag.com/male-dogs-and-the-very-young-and-old-face-higher-risk-of-severe-bites-colorado-study-finds/</link>
		
		<dc:creator><![CDATA[William Thompson]]></dc:creator>
		<pubDate>Sat, 26 Sep 2026 16:05:16 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[age-related vulnerability to dog bites]]></category>
		<category><![CDATA[analysis of dog bite incidents in Colorado]]></category>
		<category><![CDATA[Animal Behavior]]></category>
		<category><![CDATA[animal law enforcement]]></category>
		<category><![CDATA[characteristics of high-risk dog bite cases]]></category>
		<category><![CDATA[Colorado]]></category>
		<category><![CDATA[data-driven insights into dog bite severity]]></category>
		<category><![CDATA[dog bite severity risk factors]]></category>
		<category><![CDATA[dog bites]]></category>
		<category><![CDATA[epidemiology of severe dog bites in the US]]></category>
		<category><![CDATA[factors influencing dog bite injury severity]]></category>
		<category><![CDATA[harm reduction]]></category>
		<category><![CDATA[human-animal conflict and injury prevention]]></category>
		<category><![CDATA[impact of dog sex on bite outcomes]]></category>
		<category><![CDATA[injury severity]]></category>
		<category><![CDATA[logistic regression]]></category>
		<category><![CDATA[male dogs and vulnerable human age groups]]></category>
		<category><![CDATA[neutering]]></category>
		<category><![CDATA[Public health]]></category>
		<category><![CDATA[public health implications of dog bite risks]]></category>
		<category><![CDATA[research on dog-human interaction and bite severity]]></category>
		<category><![CDATA[risk factors]]></category>
		<category><![CDATA[veterinary science]]></category>
		<category><![CDATA[victim age]]></category>
		<guid isPermaLink="false">https://scienmag.com/?p=216279</guid>

					<description><![CDATA[A new analysis of over 1,100 reported dog bites in Southern Colorado finds that bites from male dogs are 81.5 percent more likely to cause severe injury in human victims, and that bite severity follows a U-shaped curve with the youngest and oldest people at greatest risk.]]></description>
										<content:encoded><![CDATA[<p>Dog bites are one of the most common injuries in the United States, yet most research has focused on a deceptively simple question: how often do they happen? A new study shifts the focus to a more consequential one — when bites do happen, what makes them worse? Analyzing 1,116 reported dog bite incidents from 2019 to 2021 in Southern Colorado, researchers Michael D. Briscoe of Colorado State University Pueblo and Shay Reszka of Colorado Mesa University found that the sex of the biting dog and the age of the human victim are strongly linked to how severe the resulting injury becomes. Their findings, published in the journal Discover Animals, challenge several long-standing assumptions about which dogs are most dangerous and offer a data-driven roadmap for reducing the worst outcomes of human-animal conflict.</p>
<p>The scale of the problem is enormous. The American Veterinary Medical Association estimates that more than 4.5 million people in the United States are bitten by dogs every year, and the Centers for Disease Control and Prevention reports that roughly 20 percent of those bites require medical attention. Beyond the human toll, the economic burden is substantial: a 1999 estimate placed the annual cost of medical care for dog bite victims between 235.6 and 253.7 million dollars, a figure that rises to between roughly 471.5 and 507.7 million dollars when adjusted to 2026 dollars. And victims are not only human. Dogs bite other dogs, and cats — because of their small size — can suffer devastating injuries from the same bite that would leave a human moderately hurt.</p>
<p>The researchers drew their data from the Humane Society of the Pikes Peak Region (HSPPR), the agency responsible for animal law enforcement in El Paso and Pueblo counties, home to Colorado Springs and Pueblo. HSPPR responds to around 2,300 calls each year about aggressive companion animals and publishes reported bites on a public &#8220;Bite Blotter.&#8221; Each victim in an incident receives a separate record, and HSPPR classifies severity in three tiers: moderate, meaning one deep puncture or multiple moderately deep punctures and lacerations; severe, meaning multiple punctures, deep gashes, serious bodily injury, or permanent disfigurement; and fatal, meaning the death of a human or domestic animal. The study region is also demographically diverse, with El Paso County&#8217;s 757,040 residents contrasting with Pueblo County&#8217;s 169,277, roughly half the bachelor&#8217;s degree attainment and double the poverty rate, which the authors argue improves the generalizability of their findings.</p>
<p>The analytical approach was deliberately more nuanced than most prior work. Instead of treating bite outcomes as a simple yes-or-no event, the researchers used ordered logistic regression on the full sample of human, dog, and cat victims, with severity as a three-level ordinal outcome. They tested the sex of the biting dog, whether the dog was spayed or neutered, an interaction between those two variables, victim species, and the location of the bite on the victim&#8217;s body. A Brant test confirmed the proportional odds assumption held for the model. For the human-only subsample, where no bites proved fatal, severity became a binary outcome of moderate versus severe, and the team turned to logistic regression, adding victim age and a quadratic age term to probe for nonlinear effects.</p>
<p>The first major result was a surprise. Across the full sample, neither the sex of the biting dog nor its alteration status showed any statistically significant association with bite severity, and the models&#8217; near-zero pseudo R-squared values confirmed that these variables were poor predictors of how bad a bite would be. What did matter enormously was the species of the victim. Compared with cat victims, dog victims had 92.8 percent lower odds of a more severe bite (odds ratio 0.072), and human victims fared even better, with odds 97.9 percent lower (odds ratio 0.021). The authors caution that reporting bias likely inflates this gap: a moderate bite to a cat may simply go unnoticed or unreported, while the same injury to a person almost certainly reaches animal control. Bite location also mattered — injuries to the torso or to multiple areas of the body were roughly three times more likely to be severe than bites to the hands, paws, arms, or front legs.</p>
<p>When the analysis narrowed to human victims only, a clearer picture emerged. Bites from male dogs carried 81.5 percent higher odds of being severe rather than moderate compared with bites from female dogs (odds ratio 1.815), an association that held consistently across every model specification. Intriguingly, whether the dog was neutered made no difference to severity — a finding that complicates the widespread assumption that spaying and neutering uniformly reduce bite risk. Prior research has documented that intact male dogs bite more often, with one study reporting an incidence rate of 55.1 bites per 1,000 unneutered males versus 3.0 per 1,000 spayed females, and testosterone described as a behavior modulator that makes dogs react more quickly, more intensely, and for longer. But frequency and severity, this study suggests, are governed by different dynamics.</p>
<p>Perhaps the study&#8217;s most striking discovery concerns victim age. Rather than a simple linear decline in risk with each passing year, the relationship between age and bite severity turned out to be distinctly U-shaped. Each additional year of age was associated with a 5.6 percent decrease in the odds of a severe bite (odds ratio 0.944), while the quadratic term was also highly significant, indicating the risk curve bends back upward. The turning point sits at just over 47 years old: before that age, risk of severe injury falls as people get older; after it, risk climbs again. A sensitivity analysis excluding the oldest one percent of victims — those over 86 — confirmed the pattern was not an artifact of a few extreme cases. Even after controlling for bite location, the U-shaped age effect remained significant, suggesting that the very young and the elderly are intrinsically more vulnerable, not merely more likely to be bitten in dangerous places like the head and neck.</p>
<p>The authors frame these findings through a harm reduction lens, an approach borrowed from public health strategies that accept a behavior will persist and aim instead to blunt its worst consequences. Dog bites, they argue, will never be eliminated as long as humans keep companion animals, so the priority should be preventing the bites that cause the most damage. This matters legally as well as medically: under Colorado law, euthanasia becomes mandatory for dogs whose bites cause serious bodily injury or death, whereas France has adopted a more rehabilitative model requiring veterinary evaluation of biting dogs within 15 days to identify triggers and prevent recurrence. In Pueblo, a new ordinance creating a &#8220;potentially dangerous animal&#8221; category now gives enforcement officers flexibility to intervene before minor incidents escalate into tragic ones.</p>
<p>The practical implications are clear. Guardians, shelters, and adoption counselors should pay particular attention to households with young children and elderly members, the two groups at the highest risk of severe injury, and supervision of dogs around these vulnerable populations should be treated as a community responsibility rather than a burden placed on individual owners. The authors also recommend that policymakers consider making responsible pet ownership education mandatory at the point of adoption or purchase, rather than only after a court order following an incident. At the same time, the study acknowledges its limits: the administrative data lacked information on breed, dog size, victim sex, and race, and many bites — especially minor ones and those involving animal victims — go unreported, sometimes because people fear that reporting could doom a dog to euthanasia. Biting, the researchers emphasize, is a natural behavior with many motivations, from fear to territoriality to predatory instinct, and understanding the patterns behind the most severe outcomes is the first step toward a world where fewer bites turn tragic.</p>
<p><strong>Subject of Research:</strong> Predictors of dog bite injury severity among human, dog, and cat victims in Southern Colorado</p>
<p><strong>Article Title:</strong> Predictors of reported dog bite injury severity among human, dog, and cat victims in Southern Colorado</p>
<p><strong>Article References:</strong> Briscoe, M. D., &amp; Reszka, S. (2026). Predictors of reported dog bite injury severity among human, dog, and cat victims in Southern Colorado. <em>Discover Animals, 3</em>(1), Article 97. <a href="https://doi.org/10.1007/s44338-026-00256-1" rel="noopener noreferrer">https://doi.org/10.1007/s44338-026-00256-1</a></p>
<p><strong>Image Credits:</strong> AI Generated</p>
<p><strong>DOI:</strong> <a href="https://doi.org/10.1007/s44338-026-00256-1" rel="noopener noreferrer">10.1007/s44338-026-00256-1</a></p>
<p><strong>Keywords:</strong> dog bites, injury severity, public health, harm reduction, animal behavior, Colorado, logistic regression, victim age, neutering, animal law enforcement, veterinary science, risk factors</p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">216279</post-id>	</item>
	</channel>
</rss>
