Oncotarget: TERT and its binding protein: overexpression of GABPA/B in gliomas
This Oncotarget study confirms the upregulation of TERT in primary glioblastomas while all GABP proteins rise with the malignancy of ...
Tag: Carcinogens
Oncotarget: Replication-stress sensitivity in breast cancer cells
Taken together these Oncotarget findings show that the CTD and OD domains of mtp53 R273H play critical roles in mutant ...
Oncotarget: Fgr and Numb in retinoic differentiation and G0 arrest of non-APL AML cells
In sum the Oncotarget data support a paradigm where signaling molecules bound to a Numb scaffold in a signalsome are ...
Hundreds of chemicals, many in consumer products, could increase breast cancer risk
List includes potential carcinogens that act by stimulating production of hormones that fuel breast tumors Every day, people are exposed ...
Oncotarget: Subtypes of thymic epithelial tumors independent of WHO type
These Oncotarget results may reflect the unselected patient population enrolled in these studies, including no selection for WHO histologic subtype ...
Oncotarget: Biomechanics in response to drug in hypoxia by atomic force spectroscopy
These Oncotarget results show that a degree of chemotherapeutic drug effects on biomechanical and biophysical properties of cancer cells is ...
Oncotarget: Caspase-11 and AIM2 inflammasome involved in COPD and lung adenocarcinoma
The Oncotarget authors found that AIM2 inflammasome is at the crossroad between COPD and lung cancer in that its higher ...
Oncotarget: Cutaneous apocrine sweat gland carcinoma
Together these Oncotarget results describe the first ever CAC case with a BRCAness genetic backgroundCredit: Correspondence to - Juha K. ...
Can turmeric reduce joint pain during breast cancer treatment?
UC Davis Comprehensive Cancer Center to study the theory, thanks to $50,000 from Safeway FoundationCredit: UC Davis Health UC Davis ...
Oncotarget: RAS reversion in colorectal cancer patients treated with bevacizumab
This Oncotarget finding might have potential therapeutic implications, as anti-EGFR could be reconsidered in primarily RAS mutant patients reverted to ...
Oncotarget: CEA as a blood-based biomarker in anal cancer
CEA is not associated with survival outcomes in SCCA, and is not a clinically relevant biomarker in this diseaseCredit: Correspondence ...
Oncotarget: LAPAS1 is required for S phase progression and cell proliferation
They identify LAPAS1 as a novel E2F-regulated lncRNA that has a potential role in human cancer and regulates cell-cycle progression ...
Oncotarget: Modulating Tau Post-translational modifications and cytoskeletal network
EGCG, a green tea polyphenol, as a modulator of in vitro methylglyoxal-induced Tau glycation and its impact on reducing advanced ...
Oncotarget: Inhibitory effects of Tomivosertib in acute myeloid leukemia
These Oncotarget findings demonstrate that Tomivosertib exhibits potent anti-leukemic properties on AML cells and support the development of clinical translational ...
Oncotarget: Urine RNA reveal tumor markers for human bladder cancer
This Oncotarget work strongly suggests exploiting urine RNAs as diagnostic markers of bladder cancer and it suggests specific novel markersCredit: ...
Banishing cigarettes into history’s ashcan
New grant expands Texas tobacco program, targets substance use patients in rural communitiesCredit: University of Houston In Texas, only 14% ...
Oncotarget: miRNA signatures from epidermal growth factor inhibitor patients
This Oncotarget study suggests that miR-21, miR-31 and miR-520e expression might be a treatment dependent marker for EGFRI induced skin ...
Oncotarget: General anesthesia for pancreatic cancer surgery
The major finding of this Oncotarget study was perioperative tryptophan depletion and increased taurine synthesis.Credit: Correspondence to - Johanna Mock-Ohnesorge ...
Oncotarget: Genome wide DNA methylation landscape reveals glioblastoma’s influence
These Oncotarget results suggest that GBM might induce epigenetic alterations in tumor infiltrating CD4 T-cellsCredit: Correspondence to - Mahua Dey ...
Oncotarget: Epithelial-mesenchymal transitions create endothelial cells and tumor growth
Cells that have undergone EMT can promote tumor growth and neovascularization either indirectly, by promoting endothelial transdifferentiation of carcinoma cells, ...
-
Dual action: RNA binding protein also binds DNA and acts as a damage sensor across the genome
-
‘Stealth transmission’ fuels fast spread of coronavirus outbreak
-
Adding SNAP benefits for older adults in Medicare, Medicaid can reduce hospital visits, healthcare costs
-
Wiggling worms suggest link between vitamin B12 and Alzheimer’s
-
Metabolism changes with age, just not when you might think