Research focused on the bioactive components of the strawberry variety Romina has shown the ability of this food to delay β-amyloid protein-induced paralysis, reduce amyloid-β aggregation and prevent oxidative stress in the experimental model Caenorhabditis elegans.
In addition, the study verified the richness of the strawberry extract used in the study in terms of its content in phenolic compounds (mainly ellagic acid and pelargonidin-3-glucoside) and minerals (K, Mg, P and Ca).
The Romina strawberry variety stands out for its high adaptability to non-fumigated soils and open field cultivation in climatic conditions from the Adriatic to central-northern Europe and for its resistance to diseases, in addition to being recognized for its nutritional quality and early ripening.
The authors of the study point out that, despite the health benefits of strawberry intake, information on the relationship of this fruit with neurodegenerative diseases, such as Alzheimer’s disease, is limited.
The research was led by the following authors: María D. Navarro-Hortal, Jose M. Romero-Márquez y Jose L. Quiles (Department of Physiology, Institute of Nutrition and Food Technology ”José Mataix”, Biomedical Research Center, University of Granada), Adelaida Esteban-Muñoz (Department of Nutrition and Bromatology, University of Granada), Cristina Sanchez-Gonzalez, Juan Llopis and Lorenzo Rivas-García (Department of Physiology, Institute of Nutrition and Food Technology ”José Mataix”, Biomedical Research Center, University of Granada; Centro de Investigación Deporte y Salud), Danila Cianciosi (Department of Biochemistry, Faculty of Science, King Abdulaziz University), Francesca Giampieri and Maurizio Battino (Department of Clinical Sciences, Università Politecnica delle Marche) Sandra Sumalla-Cano (Food, Nutritional Biochemistry and Health Research Group, European University of the Atlantic).
The full article is available in the following link.
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Strawberry (Fragaria × ananassa cv. Romina) methanolic extract attenuates Alzheimer’s beta amyloid production and oxidative stress by SKN-1/NRF and DAF-16/FOXO mediated mechanisms in C. elegans
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